Rabbit anti-Human DRAK1 Polyclonal Antibody | anti-STK17A antibody

DRAK1 Antibody

Cat. Num. AAA39989

• Gene Names: STK17A; DRAK1
• Reactivity: Human
• Applications: Immunofluorescence, Immunocytochemistry, Western Blot, ELISA
• Purity: DRAK1 Antibody is affinity chromatography purified via peptide column.
• Synonyms: DRAK1, Antibody; DRAK1 Antibody; DRAK1; DAP kinase-related apoptosis-inducing protein kinase 1; serine/threonine kinase 17a; anti-STK17A antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: No cross responses to DRAK2, DAP or ZIP kinases.
• Purity/Purification: DRAK1 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid; DRAK1 Antibody is supplied in PBS containing 0.02%
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 414

• Applicable Applications for anti-STK17A antibody: IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA
• Immunogen: DRAK1 antibody was raised against a peptide corresponding to amino acids near the amino terminus of human DRAK1.; The immunogen is located within the first 50 amino acids of DRAK1.
• Homology: Predicted species reactivity based on immunogen sequence: Rabbit: (73%)
• Preparation and Storage: DRAK1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of DRAK1 in Molt cells with DRAK1 antibody at 20 μg/mL.)

ICC (Immunocytochemistry)

(Immunocytochemistry staining of MOLT4 cells using DRAK1 antibody at 2 μg/mL.)

WB (Western Blot)

(Western blot analysis of DRAK1 in (A) MOLT4 and (B) A431 whole cell lysates with DRAK1 antibody at 1 μg/mL.)

Related Product Information for anti-STK17A antibody

DRAK1 Antibody: Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 for DAP kinase-related apoptosis-inducing protein kinases. DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain. Overexpression of DRAK1 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK1 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.

NCBI and Uniprot Product Information

• NCBI GI #: 14423930
• NCBI GeneID: 9263
• UniProt Accession #: Q9UEE5; Q8IVC8; A4D1V6
• Molecular Weight: 50 kDa
• NCBI Official Full Name: Serine/threonine-protein kinase 17A
• NCBI Official Synonym Full Names: serine/threonine kinase 17a
• NCBI Official Symbol: STK17A
• NCBI Official Synonym Symbols: DRAK1
• NCBI Protein Information: serine/threonine-protein kinase 17A; death-associated protein kinase-related 1; serine/threonine kinase 17a (apoptosis-inducing); DAP kinase-related apoptosis-inducing protein kinase 1
• UniProt Protein Name: Serine/threonine-protein kinase 17A
• UniProt Gene Name: STK17A
• UniProt Synonym Gene Names: DRAK1
• UniProt Entry Name: ST17A_HUMAN