FCM/FACS (Flow Cytometry)
(DUOX2 Antibody (Center) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Rabbit anti-Human DUOX2 Polyclonal Antibody | anti-DUOX2 antibody
DUOX2 Antibody (Center)
Gene Names
DUOX2; TDH6; LNOX2; THOX2; NOXEF2; P138-TOX
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
DUOX2, Antibody; DUOX2 Antibody (Center); Dual oxidase 2; 1111-; Large NOX 2; Long NOX 2; NADH/NADPH thyroid oxidase p138-tox; NADPH oxidase/peroxidase DUOX2; NADPH thyroid oxidase 2; Thyroid oxidase 2; p138 thyroid oxidase; DUOX2; LNOX2; THOX2; anti-DUOX2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This DUOX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 513-542 amino acids from the Central region of human DUOX2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.39 (varies by lot)
Sequence Positions
513-542
Sequence Length
1548
Applicable Applications for anti-DUOX2 antibody
FCM/FACS (Flow Cytometry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
FCM/FACS (Flow Cytometry)
(DUOX2 Antibody (Center) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
FCM/FACS (Flow Cytometry)
(DUOX2 Antibody (Center) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
WB (Western Blot)
(DUOX2 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the DUOX2 antibody detected the DUOX2 protein (arrow).)
WB (Western Blot)
(DUOX2 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the DUOX2 antibody detected the DUOX2 protein (arrow).)
Related Product Information for anti-DUOX2 antibody
The protein encoded by this gene is a glycoprotein and a
member of the NADPH oxidase family. The synthesis of thyroid
hormone is catalyzed by a protein complex located at the apical
membrane of thyroid follicular cells. This complex contains an
iodide transporter, thyroperoxidase, and a peroxide generating
system that includes this encoded protein and DUOX1. This protein
is known as dual oxidase because it has both a peroxidase homology
domain and a gp91phox domain.
member of the NADPH oxidase family. The synthesis of thyroid
hormone is catalyzed by a protein complex located at the apical
membrane of thyroid follicular cells. This complex contains an
iodide transporter, thyroperoxidase, and a peroxide generating
system that includes this encoded protein and DUOX1. This protein
is known as dual oxidase because it has both a peroxidase homology
domain and a gp91phox domain.
Product Categories/Family for anti-DUOX2 antibody
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Salmeen, A., et al. Oncogene 29(31):4473-4484(2010)
Linderholm, A.L., et al. Am. J. Physiol. Lung Cell Mol. Physiol. 299 (2), L215-L221 (2010) :
Roberts, K.E., et al. Gastroenterology 139(1):130-139(2010)
Hill, T. III, et al. Biochem. Biophys. Res. Commun. 395(2):270-274(2010)
Salmeen, A., et al. Oncogene 29(31):4473-4484(2010)
Linderholm, A.L., et al. Am. J. Physiol. Lung Cell Mol. Physiol. 299 (2), L215-L221 (2010) :
Roberts, K.E., et al. Gastroenterology 139(1):130-139(2010)
Hill, T. III, et al. Biochem. Biophys. Res. Commun. 395(2):270-274(2010)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
175364
NCBI Official Full Name
dual oxidase 2
NCBI Official Synonym Full Names
dual oxidase 2
NCBI Official Symbol
DUOX2
NCBI Official Synonym Symbols
TDH6; LNOX2; THOX2; NOXEF2; P138-TOX
NCBI Protein Information
dual oxidase 2
UniProt Protein Name
Dual oxidase 2
UniProt Gene Name
DUOX2
UniProt Synonym Gene Names
LNOX2; THOX2
UniProt Entry Name
DUOX2_HUMAN
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Product Notes
The DUOX2 duox2 (Catalog #AAA286324) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 513-542. The DUOX2 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DUOX2 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the DUOX2 duox2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DUOX2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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