WB (Western Blot)
(Western blot analysis of extracts from Huvec, using DYNC1LI2 Antibody. The lane on the left was treated with blocking peptide.)
Rabbit DYNC1LI2 Polyclonal Antibody | anti-DYNC1LI2 antibody
DYNC1LI2 Antibody
Gene Names
DYNC1LI2; LIC2; DNCLI2
Reactivity
Human, Mouse, RatPredicted: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Applications
Western Blot
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
DYNC1LI2, Antibody; DYNC1LI2 Antibody; Cytoplasmic dynein 1 light intermediate chain 2; cytosolic; DC1L2_HUMAN; DNCLI2; Dync1li2; Dynein cytoplasmic 1 light intermediate chain 2; Dynein light intermediate chain 2; dynein light intermediate chain 2 cytosolic; dynein, cytoplasmic, light intermediate polypeptide 2; LIC-2; LIC2; LIC53/55; OTTHUMP00000174820; anti-DYNC1LI2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Predicted: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Predicted: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
Clonality
Polyclonal
Isotype
IgG
Specificity
DYNC1LI2 Antibody detects endogenous levels of DYNC1LI2.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid; Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
415
Applicable Applications for anti-DYNC1LI2 antibody
WB (Western Blot)
Immunogen
A synthesized peptide derived from human DYNC1LI2.
Fragment
Fab Fragment
Conjugate
Unconjugated
Subcellular Location
Cytoskeleton
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
WB (Western Blot)
(Western blot analysis of extracts from Huvec, using DYNC1LI2 Antibody. The lane on the left was treated with blocking peptide.)
WB (Western Blot)
(Western blot analysis of extracts from Huvec, using DYNC1LI2 Antibody. The lane on the left was treated with blocking peptide.)
WB (Western Blot)
(Western blot analysis of extracts from Mouse testis tissue, using DYNC1LI2 Antibody. The lane on the left was treated with blocking peptide.)
WB (Western Blot)
(Western blot analysis of extracts from Mouse testis tissue, using DYNC1LI2 Antibody. The lane on the left was treated with blocking peptide.)
Related Product Information for anti-DYNC1LI2 antibody
Description: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
Subunit Structure: Homodimer (By similarity). The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs); the composition seems to vary in respect to the IC, LIC and LC composition. The heavy chain homodimer serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits. The ICs and LICs bind directly to the HC dimer and the LCs assemble on the IC dimer. Self-associates. Interacts with DYNC1H1; DYNC1LI1 and DYNC1LI2 bind mutually exclusive to DYNC1H1 (By similarity).
Similarity: Belongs to the dynein light intermediate chain family.
Subunit Structure: Homodimer (By similarity). The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs); the composition seems to vary in respect to the IC, LIC and LC composition. The heavy chain homodimer serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits. The ICs and LICs bind directly to the HC dimer and the LCs assemble on the IC dimer. Self-associates. Interacts with DYNC1H1; DYNC1LI1 and DYNC1LI2 bind mutually exclusive to DYNC1H1 (By similarity).
Similarity: Belongs to the dynein light intermediate chain family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 50 kDa
Predicted: 55 kDa
Predicted: 55 kDa
NCBI Official Full Name
cytoplasmic dynein 1 light intermediate chain 2 isoform 2
NCBI Official Synonym Full Names
dynein cytoplasmic 1 light intermediate chain 2
NCBI Official Symbol
DYNC1LI2
NCBI Official Synonym Symbols
LIC2; DNCLI2
NCBI Protein Information
cytoplasmic dynein 1 light intermediate chain 2
UniProt Protein Name
Cytoplasmic dynein 1 light intermediate chain 2
UniProt Gene Name
DYNC1LI2
UniProt Synonym Gene Names
DNCLI2; LIC2; LIC-2
UniProt Entry Name
DC1L2_HUMAN
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Product Notes
The DYNC1LI2 dync1li2 (Catalog #AAA328836) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DYNC1LI2 Antibody reacts with Human, Mouse, Rat Predicted: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus and may cross-react with other species as described in the data sheet. AAA Biotech's DYNC1LI2 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the DYNC1LI2 dync1li2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DYNC1LI2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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