WB (Western Blot)
(Western blot analysis of DYNLRB1 using Jurkat whole cell lysates)
Rabbit DYNLRB1 Polyclonal Antibody | anti-DYNLRB1 antibody
DYNLRB1 Antibody
Gene Names
DYNLRB1; BLP; BITH; DNCL2A; DNLC2A; ROBLD1
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
DYNLRB1, Antibody; DYNLRB1 Antibody; BITH; bithoraxoid like protein; BLP; cytoplasmic dynein light chain 2A; DNCL2A; DNLC2A; dynein associated protein HKM23; dynein associated protein Km23; Dynein light chain 2A, cytoplasmic; dynein, cytoplasmic, light polypeptide 2A; dynein, light chain, roadblock type 1; HSPC162; Roadblock 1; roadblock domain containing 1; Roadblock domain containing protein 1; ROBL/LC7 like 1; ROBLD1; anti-DYNLRB1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
DYNLRB1 antibody detects endogenous levels of total DYNLRB1
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid; Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
63
Applicable Applications for anti-DYNLRB1 antibody
ELISA, WB (Western Blot)
Immunogen
A synthesized peptide derived from human DYNLRB1, corresponding to a region within the internal amino acids.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
WB (Western Blot)
(Western blot analysis of DYNLRB1 using Jurkat whole cell lysates)
WB (Western Blot)
(Western blot analysis of DYNLRB1 using Jurkat whole cell lysates)
WB (Western Blot)
(Western blot analysis of extracts from Mouse Myeloma cell, using DYNLRB1 Antibody. Lane 1 was treated with the blocking peptide.)
WB (Western Blot)
(Western blot analysis of extracts from Mouse Myeloma cell, using DYNLRB1 Antibody. Lane 1 was treated with the blocking peptide.)
Related Product Information for anti-DYNLRB1 antibody
Function: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
Subunit Structure: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs); the composition seems to vary in respect to the IC, LIC and LC composition. The heavy chain homodimer serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits. The ICs and LICs bind directly to the HC dimer and the LCs assemble on the IC dimer. Self-associates. Interacts with DYNLRB2. Interacts with DYNC1I1 and DYNC1I2. Interacts with RAB6A isoform 1 (GTP-bound); the interaction is direct. Interacts with RAB6A isoform 2 (GDP-bound); the interaction is direct. Interacts with RAB6B (GDP-bound).
Similarity: Belongs to the GAMAD family.
Subunit Structure: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs); the composition seems to vary in respect to the IC, LIC and LC composition. The heavy chain homodimer serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits. The ICs and LICs bind directly to the HC dimer and the LCs assemble on the IC dimer. Self-associates. Interacts with DYNLRB2. Interacts with DYNC1I1 and DYNC1I2. Interacts with RAB6A isoform 1 (GTP-bound); the interaction is direct. Interacts with RAB6A isoform 2 (GDP-bound); the interaction is direct. Interacts with RAB6B (GDP-bound).
Similarity: Belongs to the GAMAD family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
11kDa
NCBI Official Full Name
dynein light chain roadblock-type 1 isoform b
NCBI Official Synonym Full Names
dynein light chain roadblock-type 1
NCBI Official Symbol
DYNLRB1
NCBI Official Synonym Symbols
BLP; BITH; DNCL2A; DNLC2A; ROBLD1
NCBI Protein Information
dynein light chain roadblock-type 1
UniProt Protein Name
Dynein light chain roadblock-type 1
UniProt Gene Name
DYNLRB1
UniProt Synonym Gene Names
BITH; DNCL2A; DNLC2A; ROBLD1; BLP
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Product Notes
The DYNLRB1 dynlrb1 (Catalog #AAA327967) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DYNLRB1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DYNLRB1 can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the DYNLRB1 dynlrb1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DYNLRB1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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