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IHC (Immunohistochemistry)
Rabbit DYRK1 Polyclonal Antibody | anti-DYRK1 antibody
DYRK1 Antibody
Gene Names
DYRK1A; MNB; DYRK; HP86; MNBH; MRD7; DYRK1
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunoprecipitation, Immunohistochemistry, ELISA
Purity
Immobilized antigen affinity chromatography
Synonyms
DYRK1, Antibody; DYRK1 Antibody; Affinity Purified Dual specificity tyrosine-phosphorylation-regulated kinase 1A Antibody; Dual specificity tyrosine phosphorylation regulated kinase; Dual specificity YAK1-related kinase; DYRK; DYRK1; DYRKA; hMNB; HP86; Minibrain, Drosophila, homolog of MNB; MNB protein kinase; Mnb protein kinase homolog hp86; MNB protein kinase, Serine/threonine-specific; MNB/DYRK protein kinase; MNBH; MRD7; Protein kinase minibrain homolog; Serine/threonine kinase MNB; anti-DYRK1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immobilized antigen affinity chromatography
Concentration
0.5 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
754
Applicable Applications for anti-DYRK1 antibody
WB (Western Blot), IP (Immunoprecipitation), IHC (Immunohistochemistry), ELISA
Immunogen
Synthetic peptide taken within amino acid region 300-350 on human Dual specificity tyrosine-phosphorylation-regulated kinase 1A.
Conjugation
Unconjugated
Molecular Function
Kinase; Serine/threonine-protein kinase; Transferase; Tyrosine-protein kinase
Subcellular Location
Nucleus Speckle
Preparation and Storage
Store at -20 degree C for long term storage.
IHC (Immunohistochemistry)
IHC (Immunohistochemistry)
IHC (Immunohistochemisry)
IHC (Immunohistochemisry)
IHC (Immunohiostchemistry)
IHC (Immunohiostchemistry)
WB (Western Blot)
WB (Western Blot)
Related Product Information for anti-DYRK1 antibody
Overview: May play a role in a signaling pathway regulating nuclear functions of cell proliferation. Modulates alternative splicing by phosphorylating the splice factor SRSF6. Phosphorylates serine, threonine and tyrosine residues in its sequence and in exogenous substrates such as CRY2, FOXO1, SRSF6 and SIRT1. Exhibits a sugstrate preference for proline at position P+1 and arginine at position P-3.
Structure: The polyhistidine repeats act as targeting signals to nuclear speckles.
Expression: Ubiquitous. Highest levels in skeletal muscle, testis, fetal lung and fetal kidney.
Structure: The polyhistidine repeats act as targeting signals to nuclear speckles.
Expression: Ubiquitous. Highest levels in skeletal muscle, testis, fetal lung and fetal kidney.
Product Categories/Family for anti-DYRK1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
66,099 Da
NCBI Official Full Name
dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform 2
NCBI Official Synonym Full Names
dual specificity tyrosine phosphorylation regulated kinase 1A
NCBI Official Symbol
DYRK1A
NCBI Official Synonym Symbols
MNB; DYRK; HP86; MNBH; MRD7; DYRK1
NCBI Protein Information
dual specificity tyrosine-phosphorylation-regulated kinase 1A
UniProt Protein Name
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
UniProt Gene Name
DYRK1A
UniProt Synonym Gene Names
DYRK; MNB; MNBH; MNBH; hMNB
Similar Products
Product Notes
The DYRK1 dyrk1a (Catalog #AAA226347) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DYRK1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DYRK1 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IP (Immunoprecipitation), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the DYRK1 dyrk1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DYRK1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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