Application Data
(Fig: Western blot analysis on A431 using anti-E-Cadherin polyclonal antibody)
anti-Mouse, Human E-Cadherin Polyclonal Antibody | anti-Cdh1 antibody
E-Cadherin Antibody
Gene Names
Cdh1; Um; UVO; Ecad; ARC-1; E-cad; L-CAM; AA960649
Reactivity
Mouse, Human
Applications
Flow Cytometry, Functional Assay, Immunocytochemistry, Western Blot
Purity
Immunogen affinity purified
Synonyms
E-Cadherin, Antibody; E-Cadherin Antibody; anti-Cdh1 antibody
Reactivity
Mouse, Human
Clonality
Polyclonal
Isotype
IgG
Specificity
This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of outside membrane of E-Cadherin.
Purity/Purification
Immunogen affinity purified
Form/Format
Liquid; 1*TBS (pH7.4), 0.5BSA, 25% Glycerol
Concentration
100ul, 0.45mg/ml (varies by lot)
Sequence Length
884
Applicable Applications for anti-Cdh1 antibody
FCM/FACS (Flow Cytometry), ICC (Immunocytochemistry), WB (Western Blot)
Preservative
0.05% Sodium Azide.
Cellular Localization
Cell Membrane
Positive Control
A431
Preparation and Storage
Store at +4 degree C after thawing. Aliquot store at-20 degree C or-80 degree C. Avoid repeated freeze/thaw cycles.
Application Data
(Fig: Western blot analysis on A431 using anti-E-Cadherin polyclonal antibody)
Application Data
(Fig: Western blot analysis on A431 using anti-E-Cadherin polyclonal antibody)
Related Product Information for anti-Cdh1 antibody
Cadherins are calcium-dependent cell adhesion proteins. The classic cadherin subfamily includes N-, P-, R-, B-and E-cadherins as well as about ten other members which are found in adherens junctions (AJ), E-cadherin is found at the junctions of epithelial cells. Besides mediating cell-cell adhesion through homophilic interactions, E-cadherin mediates contact inhibition of cell growth, and loss of E-cadherin is associated with tumorigenesis. E-cadherin expression is frequently down-regulated or extinguished in malignancy which strongly correlates with poor prognosis.
References
1. Ponta H, Hofmann M & Herrlich P. Recent advances in the genetics of metastasis. Eur J Cancer, 1.94, 3.A(1.):1.95. 2. Mareel M, Bracke M & VanRoy F. Cancer metastasis: negative regulation by an invasion-suppressor complex. Cancer Detect Prev, 1.95, 1.(5):451. 3. Nagufuchi A, Shirayoshi Y, Okazaki K, et al. Transformation of cell adhesion properties by exogenously introduced E-cadherindherin cDNA. Nature, 1.87, 3.(61.7):3.1.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
80-124kDa
NCBI Official Full Name
cadherin-1 preproprotein
NCBI Official Synonym Full Names
cadherin 1
NCBI Official Symbol
Cdh1
NCBI Official Synonym Symbols
Um; UVO; Ecad; ARC-1; E-cad; L-CAM; AA960649
NCBI Protein Information
cadherin-1
UniProt Protein Name
Cadherin-1
UniProt Gene Name
Cdh1
UniProt Synonym Gene Names
E-cadherin
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Product Notes
The Cdh1 cdh1 (Catalog #AAA110997) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The E-Cadherin Antibody reacts with Mouse, Human and may cross-react with other species as described in the data sheet. AAA Biotech's E-Cadherin can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), ICC (Immunocytochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the Cdh1 cdh1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "E-Cadherin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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