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Transfection Control
(Anti-EDNRB antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.)
Rabbit EDNRB / Endothelin B Receptor Polyclonal Antibody | anti-EDNRB antibody
Rabbit Polyclonal to Human EDNRB / Endothelin B Receptor
Gene Names
EDNRB; ETB; ET-B; ETBR; ETRB; HSCR; WS4A; ABCDS; ET-BR; HSCR2
Reactivity
Dog, HumanPredicted Reactivity: Gorilla, Gibbon (at least 90% immunogen sequence identity)
Applications
Western Blot, Immunocytochemistry, Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
EDNRB / Endothelin B Receptor, Antibody; Rabbit Polyclonal to Human EDNRB / Endothelin B Receptor; Anti-EDNRB / Endothelin B Receptor Antibody (N-Terminus) IHC-plus; EDNRB; ABCDS; Endothelin B receptor; Etb receptor; ET-B; Et-b receptor; Et-b-r; ET-RB; ETBR; ETRB; Etb-svr; WS4A; Endothelin receptor type B; ET-BR; ETB; HSCR; HSCR2; Human EDNRB; Endothelin B Receptor; anti-EDNRB antibody
Host
Rabbit
Reactivity
Dog, Human
Predicted Reactivity: Gorilla, Gibbon (at least 90% immunogen sequence identity)
Predicted Reactivity: Gorilla, Gibbon (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Specificity
Human EDNRB. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except PTPN5 (68%).
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
442
Applicable Applications for anti-EDNRB antibody
WB (Western Blot), ICC (Immunocytochemistry), IHC (Immunohistochemistry)
Target Species
Human
Immunogen Description
Synthetic 19 amino acid peptide from N-terminal extracellular domain of human EDNRB. Percent identity with other species by BLAST analysis: Human, Dog (100%); Gorilla, Gibbon (95%); Monkey (89%); Marmoset (84%).
Immunogen Type
Synthetic peptide
Immunogen
EDNRB / Endothelin B Receptor antibody was raised against synthetic 19 amino acid peptide from N-terminal extracellular domain of human EDNRB. Percent identity with other species by BLAST analysis: Human, Dog (100%); Gorilla, Gibbon (95%); Monkey (89%); Marmoset (84%).
Antigen Modification
N-Terminus
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
Transfection Control
(Anti-EDNRB antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.)
Transfection Control
(Anti-EDNRB antibody immunocytochemistry (ICC) staining of untransfected HEK293 human embryonic kidney cells.)
Transfection Control
(Anti-EDNRB antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with EDNRB.)
Transfection Control
(Anti-EDNRB antibody immunocytochemistry (ICC) staining of HEK293 human embryonic kidney cells transfected with EDNRB.)
IHC (Immunohistochemisry)
(Anti-EDNRB antibody IHC of human adrenal, medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
IHC (Immunohistochemisry)
(Anti-EDNRB antibody IHC of human adrenal, medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
IHC (Immunohiostchemistry)
(Anti-EDNRB / Endothelin B Receptor antibody IHC of human Lung, Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
IHC (Immunohiostchemistry)
(Anti-EDNRB / Endothelin B Receptor antibody IHC of human Lung, Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
IHC (Immunohistochemistry)
(Anti-EDNRB / Endothelin B Receptor antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
IHC (Immunohistochemistry)
(Anti-EDNRB / Endothelin B Receptor antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-EDNRB antibody
The Endothelin Receptor ETB is expressed in most tissues. Mutations of the receptor gene are responsible for Hirschsprung disease type 2, a multigenic disorder with phenotypes such as bicolored irides, megacolon, hypopigmentation, and hearing loss. The ETB receptor has similar affinity for all three endothelins and activates a phosphatidylinositol-calcium second messenger system.
Product Categories/Family for anti-EDNRB antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
59,480 Da
NCBI Official Full Name
endothelin B receptor isoform 1
NCBI Official Synonym Full Names
endothelin receptor type B
NCBI Official Symbol
EDNRB
NCBI Official Synonym Symbols
ETB; ET-B; ETBR; ETRB; HSCR; WS4A; ABCDS; ET-BR; HSCR2
NCBI Protein Information
endothelin B receptor; endothelin receptor non-selective type
UniProt Protein Name
Endothelin B receptor
UniProt Gene Name
EDNRB
UniProt Synonym Gene Names
ETRB; ET-B; ET-BR
UniProt Entry Name
EDNRB_HUMAN
Similar Products
Product Notes
The EDNRB ednrb (Catalog #AAA52218) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human EDNRB / Endothelin B Receptor reacts with Dog, Human Predicted Reactivity: Gorilla, Gibbon (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's EDNRB / Endothelin B Receptor can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), ICC (Immunocytochemistry), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the EDNRB ednrb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EDNRB / Endothelin B Receptor, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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