IHC (Immunohiostchemistry)
(Immunohistochemistry of EI24 in rat liver tissue with EI24 antibody at 5 μg/mL.)
Rabbit EI24 Polyclonal Antibody | anti-EI24 antibody
EI24 Antibody
Gene Names
EI24; EPG4; PIG8; TP53I8
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
EI24 Antibody is affinity chromatography purified via peptide column.
Synonyms
EI24, Antibody; EI24 Antibody; EI24; EPG4; PIG8; TP53I8; p53-induced gene 8 protein; etoposide induced 2.4 mRNA; anti-EI24 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
At least two isoforms of EI24 are known to exist; this antibody will only detect the larger isoform.
Purity/Purification
EI24 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
340
Applicable Applications for anti-EI24 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
EI24 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human EI24.
Buffer
EI24 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
EI24 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemistry of EI24 in rat liver tissue with EI24 antibody at 5 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of EI24 in rat liver tissue with EI24 antibody at 5 μg/mL.)
WB (Western Blot)
(Western blot analysis of EI24 in rat liver tissue lysate with EI24 antibody at (A) 1 and (B) 2 μg/mL.)
WB (Western Blot)
(Western blot analysis of EI24 in rat liver tissue lysate with EI24 antibody at (A) 1 and (B) 2 μg/mL.)
Related Product Information for anti-EI24 antibody
EI24 Antibody: The etoposide-induced 24 (EI24) protein is an immediate-early induction target of p53-mediated apoptosis and functions as a tumor suppressor. EI24 contains six transmembrane domains and is localized to the endoplasmic reticulum (ER). It binds to Bcl-2 and may contribute to apoptosis by modulating the activity and function of Bcl-2. EI24 is highly mutated in aggressive breast cancers and its loss in breast cancer tissue correlates with tumor invasiveness. Similar findings in invasive cervical carcinoma suggest that EI24 may be a promising therapeutic target in the treatment of invasive cancer.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
37,462 Da
NCBI Official Full Name
etoposide-induced protein 2.4 homolog isoform 1
NCBI Official Synonym Full Names
etoposide induced 2.4
NCBI Official Symbol
EI24
NCBI Official Synonym Symbols
EPG4; PIG8; TP53I8
NCBI Protein Information
etoposide-induced protein 2.4 homolog; p53-induced gene 8 protein; tumor protein p53 inducible protein 8; ectopic P-granules autophagy protein 4 homolog
UniProt Protein Name
Etoposide-induced protein 2.4 homolog
UniProt Gene Name
EI24
UniProt Synonym Gene Names
PIG8
UniProt Entry Name
EI24_HUMAN
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Product Notes
The EI24 ei24 (Catalog #AAA39340) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EI24 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's EI24 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the EI24 ei24 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EI24, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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