WB (Western Blot)
(EIF2B5 Antibody (N-term) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the EIF2B5 antibody detected the EIF2B5 protein (arrow).)
Rabbit EIF2B5 Polyclonal Antibody | anti-EIF2B5 antibody
EIF2B5 Antibody (N-term)
Gene Names
EIF2B5; CLE; CACH; LVWM; EIF-2B; EIF2Bepsilon
Reactivity
Human, mouse (Predicted Reactivity: Rat)
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
EIF2B5, Antibody; EIF2B5 Antibody (N-term); Translation initiation factor eIF-2B subunit epsilon; eIF-2B GDP-GTP exchange factor subunit epsilon; EIF2B5; EIF2BE; anti-EIF2B5 antibody
Host
Rabbit
Reactivity
Human, mouse (Predicted Reactivity: Rat)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This EIF2B5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-65 amino acids from the N-terminal region of human EIF2B5.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
36-65
Sequence Length
721
Applicable Applications for anti-EIF2B5 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(EIF2B5 Antibody (N-term) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the EIF2B5 antibody detected the EIF2B5 protein (arrow).)
WB (Western Blot)
(EIF2B5 Antibody (N-term) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the EIF2B5 antibody detected the EIF2B5 protein (arrow).)
IHC (Immunohiostchemistry)
(EIF2B5 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of EIF2B5 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(EIF2B5 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of EIF2B5 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(EIF2B5 Antibody (N-term) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the EIF2B5 antibody detected the EIF2B5 protein (arrow).)
WB (Western Blot)
(EIF2B5 Antibody (N-term) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the EIF2B5 antibody detected the EIF2B5 protein (arrow).)
Related Product Information for anti-EIF2B5 antibody
This gene encodes one of five subunits of eukaryotic
translation initiation factor 2B (EIF2B), a GTP exchange factor for
eukaryotic initiation factor 2 and an essential regulator for
protein synthesis. Mutations in this gene and the genes encoding
other EIF2B subunits have been associated with leukoencephalopathy
with vanishing white matter.
translation initiation factor 2B (EIF2B), a GTP exchange factor for
eukaryotic initiation factor 2 and an essential regulator for
protein synthesis. Mutations in this gene and the genes encoding
other EIF2B subunits have been associated with leukoencephalopathy
with vanishing white matter.
References
van der Lei, H.D., et al. Neurology 75(17):1555-1559(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Pronk, J., et al. Mult. Scler. 14(8):1123-1126(2008)
Glover, E.I., et al. Am. J. Physiol. Regul. Integr. Comp. Physiol. 295 (2), R604-R610 (2008) :
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Pronk, J., et al. Mult. Scler. 14(8):1123-1126(2008)
Glover, E.I., et al. Am. J. Physiol. Regul. Integr. Comp. Physiol. 295 (2), R604-R610 (2008) :
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
80380
NCBI Official Full Name
translation initiation factor eIF-2B subunit epsilon
NCBI Official Synonym Full Names
eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
NCBI Official Symbol
EIF2B5
NCBI Official Synonym Symbols
CLE; CACH; LVWM; EIF-2B; EIF2Bepsilon
NCBI Protein Information
translation initiation factor eIF-2B subunit epsilon
UniProt Protein Name
Translation initiation factor eIF-2B subunit epsilon
UniProt Gene Name
EIF2B5
UniProt Synonym Gene Names
EIF2BE
UniProt Entry Name
EI2BE_HUMAN
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Product Notes
The EIF2B5 eif2b5 (Catalog #AAA283768) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 36-65. The EIF2B5 Antibody (N-term) reacts with Human, mouse (Predicted Reactivity: Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's EIF2B5 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the EIF2B5 eif2b5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EIF2B5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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