IHC (Immunohistochemistry)
(Immunohistochemical staining of normal human testis tissue using ELOV4 antibody at 15 ug/ml.)
Rabbit anti-Human ELOVL4 Polyclonal Antibody | anti-ELOVL4 antibody
ELOVL4
Gene Names
ELOVL4; ADMD; CT118; ISQMR; STGD2; STGD3
Reactivity
Human
Applications
Western Blot
Purity
Antigen Immunoaffiinity Purification
Synonyms
ELOVL4, Antibody; ELOVL4; Elongation of very long chain fatty acids protein 4; ELOV4; anti-ELOVL4 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Immunoaffiinity Purification
Form/Format
Affinity Purified
Sequence Length
314
Applicable Applications for anti-ELOVL4 antibody
WB (Western Blot)
Immunogen
Synthetic peptdide derived from the human ELOV4 protein
Positive Control
Normal human testis. Expressed in the retina and at much lower level in the brain.
Preparation and Storage
Ship: Ship on gel ice, store at -20 degree C immediately upon arrival
Storage: Product should be stored at -20 degree C. Aliquot to avoid freeze/thaw cycles
Stability: Products are stable for one year from purchase when stored properly
Storage: Product should be stored at -20 degree C. Aliquot to avoid freeze/thaw cycles
Stability: Products are stable for one year from purchase when stored properly
IHC (Immunohistochemistry)
(Immunohistochemical staining of normal human testis tissue using ELOV4 antibody at 15 ug/ml.)
IHC (Immunohistochemistry)
(Immunohistochemical staining of normal human testis tissue using ELOV4 antibody at 15 ug/ml.)
Related Product Information for anti-ELOVL4 antibody
Mutations in elongation of very long-chain fatty acid-4 (ELOVL4) are associated with autosomal dominant Stargardt-like macular degeneration (STGD3), with a five base-pair (5 bp) deletion mutation resulting in the loss of 51 carboxy-terminal amino acids and truncation of the protein. Elovl4 is expressed in the retina and only a limited number of mammalian other tissues, including skin, with unknown function. In a mouse model with the 5-bp deletion in the Elovl4 gene, mice in the heterozygous state (Elovl4(+/del)) demonstrate progressive photoreceptor degeneration. Homozygous mice (Elovl4(del/del)) display scaly, wrinkled skin, have severely compromised epidermal permeability barrier function, and die within a few hours after birth. Lipid analyses of epidermis from Elovl4(del/del) mice show a decrease in very long-chain fatty acids (VLFAs) in both the ceramide/glucosylceramide and the free fatty-acid fractions. ELOVL4 is required for generating VLFA critical for epidermal barrier function.
Product Categories/Family for anti-ELOVL4 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
36829
NCBI Official Full Name
elongation of very long chain fatty acids protein 4
NCBI Official Synonym Full Names
ELOVL fatty acid elongase 4
NCBI Official Symbol
ELOVL4
NCBI Official Synonym Symbols
ADMD; CT118; ISQMR; STGD2; STGD3
NCBI Protein Information
elongation of very long chain fatty acids protein 4; ELOVL FA elongase 4; cancer/testis antigen 118; 3-keto acyl-CoA synthase ELOVL4; Stargardt disease 3 (autosomal dominant); very-long-chain 3-oxoacyl-CoA synthase 4; elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4
UniProt Protein Name
Elongation of very long chain fatty acids protein 4
UniProt Gene Name
ELOVL4
UniProt Synonym Gene Names
ELOVL FA elongase 4
UniProt Entry Name
ELOV4_HUMAN
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Product Notes
The ELOVL4 elovl4 (Catalog #AAA60502) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ELOVL4 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ELOVL4 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the ELOVL4 elovl4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ELOVL4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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