Rabbit EMILIN2 Polyclonal Antibody | anti-EMILIN2 antibody

EMILIN2 Polyclonal Antibody

Cat. Num. AAA291574

• Gene Names: EMILIN2; FOAP-10; EMILIN-2
• Reactivity: Rat, Pig, Bovine, Dog
• Applications: ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry, Western Blot
• Purity: affinity purified by Protein A
• Synonyms: EMILIN2, Antibody; EMILIN2 Polyclonal Antibody; EMILIN-2; Elastin microfibril interface-located protein 2; Elastin microfibril interfacer 2; Protein FOAP-10; EMILIN2; anti-EMILIN2 antibody

• Host: Rabbit
• Reactivity: Rat, Pig, Bovine, Dog
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Highest levels are present in fetal heart and adult lung. Intermediate levels in peripheral leukocytes, placenta, and spinal cord and low expression in fetal brain, spleen, thymus, and lung and in adult heart, aorta, testis, bone marrow, small intestine, thymus, lymph node, and appendix.
• Purity/Purification: affinity purified by Protein A
• Form/Format: 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol, 0.09% (W/V) sodium azide

• Applicable Applications for anti-EMILIN2 antibody: ELISA, ICC (Immunocytochemistry), IF (Immunofluorescence), IHC (Immunohistochemistry), IHC (Immunohistochemistry), WB (Western Blot)
• Physical State: Liquid
• Immunogen: KLH conjugated synthetic peptide derived from human EMILIN2
• Epitope Specificity: 251-350/1053
• Subcellular Location: Secreted>extracellular space>extracellular matrix. Found mainly at the interface between amorphous elastin and microfibrils.
• Similarity: Contains 1 C1q domain.Contains 1 collagen-like domain.Contains 1 EMI domain.
• Function: May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity.
• Cellular Location: Secreted, extracellular space, extracellular matrix. Note=Found mainly at the interface between amorphous elastin and microfibrils.
• Tissue Location: Highest levels are present in fetal heart and adult lung. Intermediate levels in peripheral leukocytes, placenta, and spinal cord and low expression in fetal brain, spleen, thymus, and lung and in adult heart, aorta, testis, bone marrow, small intestine, thymus, lymph node, and appendix
• Preparation and Storage: Store at -20°C for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4°C .

Related Product Information for anti-EMILIN2 antibody

EMILINs (elastin microfibril interface located proteins) are extracellular matrix glycoproteins that localize to sites with proximity to elastin and microfibrils. They consist of an N-terminal cysteine rich EMI domain and a conserved C-terminal gC1q-like domain. EMILIN-1 is abundant in elastin-rich tissues such as blood vessels, skin, heart and lung. It influences placenta formation and initial organogenesis with a later role in interstitial connective tissue. EMILIN-2 is larger than EMILIN-1 and contains a unique proline-rich domain. It is likely involved in the process of elastogenesis. Multimerin-2 (also known as EMILIN-3 or EndoGlyx-1) is expressed during embryonic development. Multimerin-1 (also known as EMILIN-4) is expressed in platelets and the endothelium of blood vessels and may act as a carrier protein for platelet factor V. EMILIN-5 is encoded by the EMILIN3 gene and is sometimes referred to as EMILIN-3. It contains the N-terminal cysteine rich EMI domain but lacks the C-terminal gC1q-like domain. EMILIN-5 is expressed in human mesenchymal stem cells and plays an important role in skeletal development.

NCBI and Uniprot Product Information

• NCBI GI #: 60498978
• NCBI GeneID: 84034
• NCBI Accession #: NP_114437.2
• NCBI GenBank Nucleotide #: NM_032048.2
• UniProt Accession #: Q9BXX0; Q8NBH3; Q96JQ4; B2RMY3
• Molecular Weight: Calculated MW: 112 KDa
• NCBI Official Full Name: EMILIN-2
• NCBI Official Synonym Full Names: elastin microfibril interfacer 2
• NCBI Official Symbol: EMILIN2
• NCBI Official Synonym Symbols: FOAP-10; EMILIN-2
• NCBI Protein Information: EMILIN-2; extracellular glycoprotein EMILIN-2; elastin microfibril interface-located protein 2
• UniProt Protein Name: EMILIN-2
• UniProt Gene Name: EMILIN2
• UniProt Synonym Gene Names: Elastin microfibril interfacer 2
• UniProt Entry Name: EMIL2_HUMAN