Rabbit EMX2 Polyclonal Antibody | anti-EMX2 antibody

EMX2 Antibody (Center)

Cat. Num. AAA285263

• Reactivity: Human (Predicted Reactivity: Bovine, Mouse)
• Applications: Flow Cytometry, Functional Assay, ELISA, Western Blot
• Purity: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Synonyms: EMX2, Antibody; EMX2 Antibody (Center); Homeobox protein EMX2; Empty spiracles homolog 2; Empty spiracles-like protein 2; EMX2; anti-EMX2 antibody

• Host: Rabbit
• Reactivity: Human (Predicted Reactivity: Bovine, Mouse)
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Specificity: This EMX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-138 amino acids from the Central region of human EMX2.
• Purity/Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Form/Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
• Sequence Positions: 111-138
• Sequence Length: 169

• Applicable Applications for anti-EMX2 antibody: FCM/FACS (Flow Cytometry), ELISA, WB (Western Blot)
• Preparation and Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

FCM/FACS (Flow Cytometry)

(EMX2 Antibody (Center) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

WB (Western Blot)

(EMX2 Antibody (Center) western blot analysis in HL-60 cell line lysates (15ug/lane).This demonstrates the EMX2 antibody detected the EMX2 protein (arrow).)

Related Product Information for anti-EMX2 antibody

This gene encodes a homeobox-containing transcription factor that is the homolog to the 'empty spiracles' gene in Drosophila. Research on this gene in humans has focused on its expression in three tissues: dorsal telencephalon, olfactory neuroepithelium, and urogenetial system. It is expressed in the dorsal telencephalon during development in a low rostral-lateral to high caudal-medial gradient and is proposed to pattern the neocortex into defined functional areas. It is also expressed in embryonic and adult olfactory neuroepithelia where it complexes with eukaryotic translation initiation factor 4E (eIF4E) and possibly regulates mRNA transport or translation. In the developing urogenital system, it is expressed in epithelial tissues and is negatively regulated by HOXA10. Alternative splicing results in multiple transcript variants encoding distinct proteins.

Product Categories/Family for anti-EMX2 antibody

Neuroscience

References

Inkster, B., et al. Neuroimage (2010) In press :
Bayatti, N., et al. Eur. J. Neurosci. 28(8):1449-1456(2008)
Merello, E., et al. Am. J. Med. Genet. A 146A (9), 1142-1150 (2008) :
Treloar, S.A., et al. Mol. Hum. Reprod. 13(8):587-594(2007)

NCBI and Uniprot Product Information

• NCBI GI #: 260064072
• NCBI GeneID: 2018
• NCBI Accession #: NP_001159396.1; NP_004089.1
• NCBI GenBank Nucleotide #: NM_001165924.1
• UniProt Accession #: Q04743; Q96NN8; Q9BQF4; G3V305
• Molecular Weight: 28303
• NCBI Official Full Name: homeobox protein EMX2 isoform 2
• NCBI Official Synonym Full Names: empty spiracles homeobox 2
• NCBI Official Symbol: EMX2
• NCBI Protein Information: homeobox protein EMX2
• UniProt Protein Name: Homeobox protein EMX2
• UniProt Gene Name: EMX2
• UniProt Entry Name: EMX2_HUMAN