IHC (Immunohistochemisry)
(Dilution: IHC-p 1:50-200, ELISA 1:10000-20000)
Rabbit EphB3 Polyclonal Antibody | anti-EphB3 antibody
EphB3 Polyclonal Antibody
Gene Names
EPHB3; ETK2; HEK2; TYRO6
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry
Synonyms
EphB3, Antibody; EphB3 Polyclonal Antibody; Ephrin type-B receptor 3 (EC 2.7.10.1)(EPH-like tyrosine kinase 2)(EPH-like kinase 2)(Embryonic kinase 2)(EK2)(hEK2)(Tyrosine-protein kinase TYRO6); anti-EphB3 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Applicable Applications for anti-EphB3 antibody
IHC (Immunohistochemistry)
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohistochemisry)
(Dilution: IHC-p 1:50-200, ELISA 1:10000-20000)
IHC (Immunohistochemisry)
(Dilution: IHC-p 1:50-200, ELISA 1:10000-20000)
IHC (Immunohiostchemistry)
(Dilution: IHC-p 1:50-200, ELISA 1:10000-20000)
IHC (Immunohiostchemistry)
(Dilution: IHC-p 1:50-200, ELISA 1:10000-20000)
IHC (Immunohistochemistry)
(Dilution: IHC-p 1:50-200, ELISA 1:10000-20000)
IHC (Immunohistochemistry)
(Dilution: IHC-p 1:50-200, ELISA 1:10000-20000)
Related Product Information for anti-EphB3 antibody
Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Generally has an overlapping and redundant function with EPHB2. Like EPHB2, functions in axon guidance during development regulating for instance the neurons forming the corpus callosum and the anterior commissure, 2 major interhemispheric connections between the temporal lobes of the cerebral cortex. In addition to its role in axon guidance plays also an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and the formation of excitatory synapses. Controls other aspects of development through regulation of cell migration and positioning. This includes angiogenesis, palate development and thymic epithelium development for instance. Forward and reverse signaling through the EFNB2/EPHB3 complex also regulate migration and adhesion of cells that tubularize the urethra and septate the cloaca. Finally, plays an important role in intestinal epithelium differentiation segregating progenitor from differentiated cells in the crypt.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
110,330 Da
NCBI Official Full Name
Ephrin type-B receptor 3
NCBI Official Synonym Full Names
EPH receptor B3
NCBI Official Symbol
EPHB3
NCBI Official Synonym Symbols
ETK2; HEK2; TYRO6
NCBI Protein Information
ephrin type-B receptor 3; EK2; EPH-like kinase 2; embryonic kinase 2; human embryo kinase 2; EPH-like tyrosine kinase 2; EPH-like tyrosine kinase-2; tyrosine-protein kinase TYRO6
UniProt Protein Name
Ephrin type-B receptor 3
UniProt Gene Name
EPHB3
UniProt Synonym Gene Names
ETK2; HEK2; TYRO6; EPH-like kinase 2; EK2; hEK2
UniProt Entry Name
EPHB3_HUMAN
Similar Products
Product Notes
The EphB3 ephb3 (Catalog #AAA296622) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EphB3 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's EphB3 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the EphB3 ephb3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EphB3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.