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product-image-AAA39383_IF11.jpg IF (Immunofluorescence) (Immunofluorescence of EPM2A in SW480 cells with EPM2A antibody at 5 μg/ml.)

Rabbit EPM2A Polyclonal Antibody | anti-EPM2A antibody

EPM2A Antibody

Gene Names
EPM2A; EPM2; MELF
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunocytochemistry, Western Blot, ELISA
Purity
EPM2A Antibody is affinity chromatography purified via peptide column.
Synonyms
EPM2A, Antibody; EPM2A Antibody; EPM2A; EPM2; MELF; Laforin; Lafora PTPase; LAFPTPase; epilepsy, progressive myoclonus type 2A, Lafora disease (laforin); anti-EPM2A antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
At least four isoforms of EPM2A are known to exist; this antibody will detect all but the shortest isoform.
Purity/Purification
EPM2A Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
331
Applicable Applications for anti-EPM2A antibody
IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
EPM2A antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human EPM2A.
Buffer
EPM2A Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
EPM2A antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of EPM2A in SW480 cells with EPM2A antibody at 5 μg/ml.)

product-image-AAA39383_IF11.jpg IF (Immunofluorescence) (Immunofluorescence of EPM2A in SW480 cells with EPM2A antibody at 5 μg/ml.)

ICC (Immunocytochemistry)

(Immunocytochemistry of EPM2A in SW480 cells with EPM2A antibody at 2.5 μg/ml.)

product-image-AAA39383_ICC13.jpg ICC (Immunocytochemistry) (Immunocytochemistry of EPM2A in SW480 cells with EPM2A antibody at 2.5 μg/ml.)

WB (Western Blot)

(Western blot analysis of SW480 in SW480 cell lysate with EPM2A antibody at (A) 1 and (B) 2 μg/mL.)

product-image-AAA39383_WB15.gif WB (Western Blot) (Western blot analysis of SW480 in SW480 cell lysate with EPM2A antibody at (A) 1 and (B) 2 μg/mL.)
Related Product Information for anti-EPM2A antibody
EPM2A Antibody: The Epilepsy, progressive myoclonus type 2A protein (EPM2A) is a dual-specificity phosphatase that associates with polyribosomes. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. EPM2A interacts with a number of proteins known to be involved in glycogen metabolism and has been shown to have robust phosphatase activity against a phosphorylated complex carbohydrate, suggesting that EPM2A may be involved in the regulation of glycogen metabolism.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
36 kDa
NCBI Official Full Name
laforin isoform a
NCBI Official Synonym Full Names
epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
NCBI Official Symbol
EPM2A
NCBI Official Synonym Symbols
EPM2; MELF
NCBI Protein Information
laforin; EPM2A; LAFPTPase; lafora PTPase; glucan phosphatase; epilepsy, progressive myoclonus type 2, Lafora disease (laforin)
UniProt Protein Name
Laforin
UniProt Gene Name
EPM2A
UniProt Synonym Gene Names
LAFPTPase
UniProt Entry Name
EPM2A_HUMAN

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Product Notes

The EPM2A epm2a (Catalog #AAA39383) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EPM2A Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's EPM2A can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the EPM2A epm2a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EPM2A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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