IHC (Immunohiostchemistry)
(ERCC8 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ERCC8 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human, mouse ERCC8 Polyclonal Antibody | anti-ERCC8 antibody
ERCC8 Antibody (Center)
Gene Names
ERCC8; CSA; CKN1; UVSS2
Reactivity
Human, mouse
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
ERCC8, Antibody; ERCC8 Antibody (Center); DNA excision repair protein ERCC-8; Cockayne syndrome WD repeat protein CSA; ERCC8; CKN1; CSA; anti-ERCC8 antibody
Host
Rabbit
Reactivity
Human, mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This ERCC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-238 amino acids from the Central region of human ERCC8.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
210-238
Sequence Length
205
Applicable Applications for anti-ERCC8 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(ERCC8 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ERCC8 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(ERCC8 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ERCC8 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(ERCC8 Antibody (Center) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the ERCC8 antibody detected the ERCC8 protein (arrow).)
WB (Western Blot)
(ERCC8 Antibody (Center) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the ERCC8 antibody detected the ERCC8 protein (arrow).)
Related Product Information for anti-ERCC8 antibody
This gene encodes a WD repeat protein, which interacts
with Cockayne syndrome type B (CSB) protein and with p44 protein, a
subunit of the RNA polymerase II transcription factor IIH.
Mutations in this gene have been identified in patients with
hereditary disease Cockayne syndrome (CS). CS cells are abnormally
sensitive to ultraviolet radiation and are defective in the repair
of transcriptionally active genes.
with Cockayne syndrome type B (CSB) protein and with p44 protein, a
subunit of the RNA polymerase II transcription factor IIH.
Mutations in this gene have been identified in patients with
hereditary disease Cockayne syndrome (CS). CS cells are abnormally
sensitive to ultraviolet radiation and are defective in the repair
of transcriptionally active genes.
References
Briggs, F.B., et al. Am. J. Epidemiol. 172(2):217-224(2010)
Guillem, V.M., et al. Am. J. Hematol. 85(7):482-486(2010)
Monsees, G.M., et al. Breast Cancer Res. Treat. (2010) In press :
Kamenisch, Y., et al. J. Exp. Med. 207(2):379-390(2010)
Laugel, V., et al. Hum. Mutat. 31(2):113-126(2010)
Guillem, V.M., et al. Am. J. Hematol. 85(7):482-486(2010)
Monsees, G.M., et al. Breast Cancer Res. Treat. (2010) In press :
Kamenisch, Y., et al. J. Exp. Med. 207(2):379-390(2010)
Laugel, V., et al. Hum. Mutat. 31(2):113-126(2010)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
44055
NCBI Official Full Name
DNA excision repair protein ERCC-8 isoform 1
NCBI Official Synonym Full Names
excision repair cross-complementation group 8
NCBI Official Symbol
ERCC8
NCBI Official Synonym Symbols
CSA; CKN1; UVSS2
NCBI Protein Information
DNA excision repair protein ERCC-8
UniProt Protein Name
DNA excision repair protein ERCC-8
UniProt Gene Name
ERCC8
UniProt Synonym Gene Names
CKN1; CSA
UniProt Entry Name
ERCC8_HUMAN
Similar Products
Product Notes
The ERCC8 ercc8 (Catalog #AAA286799) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 210-238. The ERCC8 Antibody (Center) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's ERCC8 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the ERCC8 ercc8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ERCC8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.