WB (Western Blot)
(Detection of mouse EXOSC1 by western blot. Samples: Whole cell lysate (15 and 50 ug) from mouse NIH 3T3 cells. Antibodies: Affinity purified rabbit anti-EXOSC1 antibody AAA212346 (lot AAA212346-1) used for WB at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.)
Rabbit anti-Human, Mouse EXOSC1 Polyclonal Antibody | anti-EXOSC1 antibody
Rabbit anti-EXOSC1 Antibody, Affinity Purified
Gene Names
EXOSC1; p13; CSL4; SKI4; Csl4p; Ski4p; hCsl4p; CGI-108
Reactivity
Human, Mouse
Applications
Immunoprecipitation, Western Blot
Purity
Antigen Affinity Purified
Synonyms
EXOSC1, Antibody; Rabbit anti-EXOSC1 Antibody, Affinity Purified; Exosome component 1; SKI4; Ski4p; p13; homolog of yeast exosomal core protein CSL4; exosome complex component CSL4; exosomal core protein CSL4; Csl4p; CSL4; 3'-5' exoribonuclease CSL4 homolog; CGI-108; Exosome complex component CSL4; exosome component 1; anti-EXOSC1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Concentration
1000ug/ml (varies by lot)
Applicable Applications for anti-EXOSC1 antibody
IP (Immunoprecipitation), WB (Western Blot)
Immunogen
Between 145 and C-terminus
Conjugation
Unconjugated
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Shelf Life: 1 year from date of receipt
WB (Western Blot)
(Detection of mouse EXOSC1 by western blot. Samples: Whole cell lysate (15 and 50 ug) from mouse NIH 3T3 cells. Antibodies: Affinity purified rabbit anti-EXOSC1 antibody AAA212346 (lot AAA212346-1) used for WB at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.)
WB (Western Blot)
(Detection of mouse EXOSC1 by western blot. Samples: Whole cell lysate (15 and 50 ug) from mouse NIH 3T3 cells. Antibodies: Affinity purified rabbit anti-EXOSC1 antibody AAA212346 (lot AAA212346-1) used for WB at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.)
WB (Western Blot)
(Detection of human EXOSC1 by western blot. Samples: Whole cell lysate from HeLa (15 and 50 ug), HEK293T (50ug), and Jurkat (50ug) cells. Antibodies: Affinity purified rabbit anti-EXOSC1 antibody AAA212346 (lot AAA212346-1) used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.)
WB (Western Blot)
(Detection of human EXOSC1 by western blot. Samples: Whole cell lysate from HeLa (15 and 50 ug), HEK293T (50ug), and Jurkat (50ug) cells. Antibodies: Affinity purified rabbit anti-EXOSC1 antibody AAA212346 (lot AAA212346-1) used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.)
IP (Immunoprecipitation)
(Detection of human EXOSC1 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-EXOSC1 antibody AAA212346 (lot AAA212346-1) used for IP at 6 ug/mg lysate. EXOSC1 was also immunoprecipitated by rabbit anti-EXOSC1 antibody BL13999. For blotting immunoprecipitated EXOSC1, AAA212346 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.)
IP (Immunoprecipitation)
(Detection of human EXOSC1 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-EXOSC1 antibody AAA212346 (lot AAA212346-1) used for IP at 6 ug/mg lysate. EXOSC1 was also immunoprecipitated by rabbit anti-EXOSC1 antibody BL13999. For blotting immunoprecipitated EXOSC1, AAA212346 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.)
Related Product Information for anti-EXOSC1 antibody
EXOSC1 is a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association CSL4 with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46 [taken from NCBI Entrez Gene (Gene ID: 51013)].
Product Categories/Family for anti-EXOSC1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
21,452 Da
NCBI Official Full Name
exosome complex component CSL4
NCBI Official Synonym Full Names
exosome component 1
NCBI Official Symbol
EXOSC1
NCBI Official Synonym Symbols
p13; CSL4; SKI4; Csl4p; Ski4p; hCsl4p; CGI-108
NCBI Protein Information
exosome complex component CSL4; exosomal core protein CSL4; 3'-5' exoribonuclease CSL4 homolog; CSL4 exosomal core protein homolog; homolog of yeast exosomal core protein CSL4
UniProt Protein Name
Exosome complex component CSL4
UniProt Gene Name
EXOSC1
UniProt Synonym Gene Names
CSL4
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Product Notes
The EXOSC1 exosc1 (Catalog #AAA212346) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-EXOSC1 Antibody, Affinity Purified reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's EXOSC1 can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), WB (Western Blot). Researchers should empirically determine the suitability of the EXOSC1 exosc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EXOSC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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