IHC (Immunohiostchemistry)
(F11 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of F11 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human F11 Polyclonal Antibody | anti-F11 antibody
F11 Antibody (Center)
Gene Names
F11; FXI
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
F11, Antibody; F11 Antibody (Center); Coagulation factor XI; FXI; Plasma thromboplastin antecedent; PTA; Coagulation factor XIa heavy chain; Coagulation factor XIa light chain; F11; anti-F11 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This F11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-307 amino acids from the Central region of human F11.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.45 (varies by lot)
Sequence Positions
281-307
Sequence Length
625
Applicable Applications for anti-F11 antibody
WB (Western Blot), IHC (Immunohistochemistry), ELISA
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(F11 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of F11 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(F11 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of F11 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(F11 Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the F11 antibody detected the F11 protein (arrow).)
WB (Western Blot)
(F11 Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the F11 antibody detected the F11 protein (arrow).)
Related Product Information for anti-F11 antibody
This gene encodes coagulation factor XI of the blood
coagulation cascade. This protein is present in plasma as a
zymogen, which is a unique plasma coagulation enzyme because it
exists as a homodimer consisting of two identical polypeptide
chains linked by disulfide bonds. During activation of the plasma
factor XI, an internal peptide bond is cleaved by factor XIIa (or
XII) in each of the two chains, resulting in activated factor XIa,
a serine protease composed of two heavy and two light chains held
together by disulfide bonds. This activated plasma factor XI
triggers the middle phase of the intrisic pathway of blood
coagulation by activating factor IX. Defects in this factor lead to
Rosenthal syndrome, a blood coagulation abnormality. [provided by
RefSeq].
coagulation cascade. This protein is present in plasma as a
zymogen, which is a unique plasma coagulation enzyme because it
exists as a homodimer consisting of two identical polypeptide
chains linked by disulfide bonds. During activation of the plasma
factor XI, an internal peptide bond is cleaved by factor XIIa (or
XII) in each of the two chains, resulting in activated factor XIa,
a serine protease composed of two heavy and two light chains held
together by disulfide bonds. This activated plasma factor XI
triggers the middle phase of the intrisic pathway of blood
coagulation by activating factor IX. Defects in this factor lead to
Rosenthal syndrome, a blood coagulation abnormality. [provided by
RefSeq].
Product Categories/Family for anti-F11 antibody
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Wong, P.C., et al. Thromb. Haemost. 104(2):302-310(2010)
Whelihan, M.F., et al. J. Thromb. Haemost. 8(7):1532-1539(2010)
Delluc, A., et al. Thromb. Haemost. 103(6):1161-1169(2010)
Barber, M.J., et al. PLoS ONE 5 (3), E9763 (2010) :
Wong, P.C., et al. Thromb. Haemost. 104(2):302-310(2010)
Whelihan, M.F., et al. J. Thromb. Haemost. 8(7):1532-1539(2010)
Delluc, A., et al. Thromb. Haemost. 103(6):1161-1169(2010)
Barber, M.J., et al. PLoS ONE 5 (3), E9763 (2010) :
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
70109
NCBI Official Full Name
coagulation factor XI
NCBI Official Synonym Full Names
coagulation factor XI
NCBI Official Symbol
F11
NCBI Official Synonym Symbols
FXI
NCBI Protein Information
coagulation factor XI
UniProt Protein Name
Coagulation factor XI
UniProt Gene Name
F11
UniProt Synonym Gene Names
FXI; PTA
UniProt Entry Name
FA11_HUMAN
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Product Notes
The F11 f11 (Catalog #AAA283687) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 281-307. The F11 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's F11 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the F11 f11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "F11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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