Host
Rabbit
Reactivity
Ubiquitous
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Ammonium Sulfate Precipitation
Form/Format
Unconjugated
Sequence Length
419
Applicable Applications for anti-FDPS antibody
IF (Immunofluorescence), ELISA
Immunogen
Antibody developed using farnesyl cysteine conjugated to KLH.
Preparation and Storage
Product should be stored at -20 degree C. Aliquot to avoid freeze/thaw cycles
Ship Conditions: Ship at ambient temperature, freeze upon arrival.
Products are stable for one year from purchase when stored properly.
Ship Conditions: Ship at ambient temperature, freeze upon arrival.
Products are stable for one year from purchase when stored properly.
Related Product Information for anti-FDPS antibody
Protein isoprenylation is a post-translational modification that affects about 0.5% of cellular proteins and is essential for the biological activity of proteins. Two enzymes catalyze the attachment of two prenyl groups to the sulfhydryl group of carboxyl-terminal cysteine groups. Proteins which are prenylated by these enzymes have a distinct motif at the C-terminal of the protein, C-A1-A2-X (C = Cysteine, A1 & A2 = aliphatic amino acids). The two enzymes involved in this transfer are farnesyltransferase and geranylgeranyltransferase. These transfer a 15 carbon farnesyl or a 20 carbon geranygeranyl, respectively, from a prenyl-pyrophosphate to the protein. Examples of proteins containing this C-A-A-X motif are members of the Ras small G protein family, the nuclear lamins and the gamma subunit of trimeric G proteins. Prenylation of proteins is necessary for membrane association of proteins as well as protein-protein interactions and the nature of the linked isoprenyl group can influence the protein interactions, such as the interaction between G proteins and receptors.
Product Categories/Family for anti-FDPS antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
48,275 Da
NCBI Official Full Name
farnesyl pyrophosphate synthase isoform a
NCBI Official Synonym Full Names
farnesyl diphosphate synthase
NCBI Official Symbol
FDPS
NCBI Official Synonym Symbols
FPS; FPPS
NCBI Protein Information
farnesyl pyrophosphate synthase; FPP synthase; FPP synthetase; geranyltranstransferase; dimethylallyltranstransferase; (2E,6E)-farnesyl diphosphate synthase; farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase
UniProt Protein Name
Farnesyl pyrophosphate synthase
UniProt Gene Name
FDPS
UniProt Synonym Gene Names
FPS; KIAA1293; FPP synthase; FPS
UniProt Entry Name
FPPS_HUMAN
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Product Notes
The FDPS fdps (Catalog #AAA60505) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Farnesyl reacts with Ubiquitous and may cross-react with other species as described in the data sheet. AAA Biotech's Farnesyl can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), ELISA. Researchers should empirically determine the suitability of the FDPS fdps for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Farnesyl, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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