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product-image-AAA225684_WB13.jpg WB (Western Blot) (Lane 1: MCF-7 Cell Lysate; Lane 2: Hela Cell Lysate; Lane 3: MM231 Cell Lysate; Lane 4: Jurkat Cell Lysate; Lane 5: HT1080 Cell Lysate; Lane 6: Colo320 Cell Lysate)

Rabbit FASL Polyclonal Antibody | anti-FASL antibody

FASL Antibody

Gene Names
FASLG; FasL
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Purity
Affinity Chromatography
Synonyms
FASL, Antibody; FASL Antibody; Affinity Purified Goat Polyclonal FASL Antibody; Polyclonal FASL antibody; Anti-FASL antibody; TNFSF6 antibody; sFASL antibody; Apo I Ligand antibody; CD95L antibody; APTL antibody; soluble Fas Ligand antibody; anti-FASL antibody
Ordering
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Chromatography
Form/Format
Lyophilized Form
Sequence Length
277
Applicable Applications for anti-FASL antibody
ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
FASL antibody was raised in Rabbit using a synthetic peptide corresponding to a sequence at the C-terminal of human FAS-L, different from the related Rabbit sequence by two amino acids, and from the related rat sequence by three amino acids, as the immunogen
Preparation and Storage
Store at 4 degree C for short term storage. For long term storage aliquot and store at -20 degree C. Avoid repeated freeze/thaw cycles.

WB (Western Blot)

(Lane 1: MCF-7 Cell Lysate; Lane 2: Hela Cell Lysate; Lane 3: MM231 Cell Lysate; Lane 4: Jurkat Cell Lysate; Lane 5: HT1080 Cell Lysate; Lane 6: Colo320 Cell Lysate)

product-image-AAA225684_WB13.jpg WB (Western Blot) (Lane 1: MCF-7 Cell Lysate; Lane 2: Hela Cell Lysate; Lane 3: MM231 Cell Lysate; Lane 4: Jurkat Cell Lysate; Lane 5: HT1080 Cell Lysate; Lane 6: Colo320 Cell Lysate)

IHC (Immunohistochemistry)

(Immunohistochemistry of paraffin-embedded section of Human Intestinal Cancer Tissue)

product-image-AAA225684_IHC15.jpg IHC (Immunohistochemistry) (Immunohistochemistry of paraffin-embedded section of Human Intestinal Cancer Tissue)
Related Product Information for anti-FASL antibody
Fas and Fas Ligand (FASL) belong to the TNF superfamily and are type I and type II transmembrane proteins, respectively. Binding of FASL to Fas triggers apoptosis in Fas-bearing cells. The mechanism of apoptosis involves recruitment of pro-caspase 8 through an adaptor molecule called FADD followed by processing of the pro-enzyme to active forms. These active caspases then cleave various cellular substrates leading to the eventual cell death. sFasR is capable of inhibiting FASL-induced apoptosis by acting as a decoy receptor that serves as a sink for FASL.
Product Categories/Family for anti-FASL antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Official Full Name
FasL
NCBI Official Symbol
FASLG
NCBI Official Synonym Symbols
FasL
NCBI Protein Information
tumor necrosis factor ligand superfamily member 6

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Product Notes

The FASL (Catalog #AAA225684) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's FASL can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the FASL for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FASL, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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