IHC (Immunohistochemisry)
(Anti-FER antibody, AAA45460, IHC(P)IHC(P): Rat Intestine Tissue)
Rabbit anti-Human, Rat FER Polyclonal Antibody | anti-FER antibody
Anti-FER antibody
Gene Names
FER; FerT; TYK3; Pe1Fe3; Pe1Fe6; PPP1R74; Pe1Fe10; Pe1Fe13
Reactivity
Human, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
FER, Antibody; Anti-FER antibody; Tyrosine-protein kinase Fer; fer(fps/fes related) tyrosine kinase; c FER antibody; Fer(fps/fes related) tyrosine kinase(phosphoprotein NCP94) antibody; Fer(fps/fes related) tyrosine kinase antibody; FER antibody; FER_HUMAN antibody; p94 FER antibody; p94-FER antibody; Phosphoprotein NCP94 antibody; Proto oncogene tyrosine protein kinase FER antibody; Proto-oncogene c-Fer antibody; TYK3 antibody; Tyrosine kinase 3 antibody; Tyrosine-protein kinase Fer antibody; anti-FER antibody
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
822
Applicable Applications for anti-FER antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human FER (521-536aa FSNIPQLIDHHYTTKQ), different from the related rat and mouse sequences by two amino acids.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohistochemisry)
(Anti-FER antibody, AAA45460, IHC(P)IHC(P): Rat Intestine Tissue)
IHC (Immunohistochemisry)
(Anti-FER antibody, AAA45460, IHC(P)IHC(P): Rat Intestine Tissue)
IHC (Immunohiostchemistry)
(Anti-FER antibody, AAA45460, IHC(P)IHC(P): Human Intestinal Cancer Tissue)
IHC (Immunohiostchemistry)
(Anti-FER antibody, AAA45460, IHC(P)IHC(P): Human Intestinal Cancer Tissue)
WB (Western Blot)
(Anti-FER antibody, AAA45460, Western blottingAll lanes: Anti FER (AAA45460) at 0.5ug/mlLane 1: HELA Whole Cell Lysate at 40ugLane 2: Rat Testis Tissue Lysate at 50ugLane 3: Rat Ovary Tissue Lysate at 50ugPredicted bind size: 95KDObserved bind size: 95KD)
WB (Western Blot)
(Anti-FER antibody, AAA45460, Western blottingAll lanes: Anti FER (AAA45460) at 0.5ug/mlLane 1: HELA Whole Cell Lysate at 40ugLane 2: Rat Testis Tissue Lysate at 50ugLane 3: Rat Ovary Tissue Lysate at 50ugPredicted bind size: 95KDObserved bind size: 95KD)
Related Product Information for anti-FER antibody
Description: Rabbit IgG polyclonal antibody for Tyrosine-protein kinase Fer(FER) detection. Tested with WB, IHC-P in Human, Rat.
Background: FER(FPS/FES-Related tyrosine kinase) also known as TYK3, is an enzyme that in humans is encoded by the FER gene. Fer protein is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases. By in situ hybridization, Morris et al.(1990) concluded that the FER gene is located at 5q21-q22. Treatment of cells with JMP resulted in the release of FER from the cadherin complex and its accumulation in the integrin complex. The accumulation of FER in the integrin complex and the inhibitory effects of JMP could be reversed with a peptide that mimics the first coiled-coil domain of FER. The results suggested that FER mediates crosstalk between CDH2 and ITGB1. In Fer mutant mice, leukocyte emigration was exaggerated in response to LPS without altering vascular permeability, suggesting that FER has a role in regulating innate immunity.
Background: FER(FPS/FES-Related tyrosine kinase) also known as TYK3, is an enzyme that in humans is encoded by the FER gene. Fer protein is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases. By in situ hybridization, Morris et al.(1990) concluded that the FER gene is located at 5q21-q22. Treatment of cells with JMP resulted in the release of FER from the cadherin complex and its accumulation in the integrin complex. The accumulation of FER in the integrin complex and the inhibitory effects of JMP could be reversed with a peptide that mimics the first coiled-coil domain of FER. The results suggested that FER mediates crosstalk between CDH2 and ITGB1. In Fer mutant mice, leukocyte emigration was exaggerated in response to LPS without altering vascular permeability, suggesting that FER has a role in regulating innate immunity.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
51,643 Da
NCBI Official Full Name
Tyrosine-protein kinase Fer
NCBI Official Synonym Full Names
fer (fps/fes related) tyrosine kinase
NCBI Official Symbol
FER
NCBI Official Synonym Symbols
FerT; TYK3; Pe1Fe3; Pe1Fe6; PPP1R74; Pe1Fe10; Pe1Fe13
NCBI Protein Information
tyrosine-protein kinase Fer; p94-Fer; tyrosine kinase 3; phosphoprotein NCP94; proto-oncogene c-Fer; feline encephalitis virus-related kinase FER; protein phosphatase 1, regulatory subunit 74; truncated fer (fps/fes related) tyrosine kinase; fujinami poultry sarcoma/Feline sarcoma-related protein Fer
UniProt Protein Name
Tyrosine-protein kinase Fer
UniProt Gene Name
FER
UniProt Synonym Gene Names
TYK3
UniProt Entry Name
FER_HUMAN
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Product Notes
The FER fer (Catalog #AAA45460) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-FER antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's FER can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the FER fer for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FER, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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