Goat FHL1 Polyclonal Antibody | anti-FHL1 antibody

GOAT ANTI HUMAN FHL1

Cat. Num. AAA50081

• Gene Names: FHL1; KYOT; SLIM; FHL-1; FHL1A; FHL1B; FLH1A; SLIM1; XMPMA; SLIM-1; SLIMMER
• Reactivity: Bovine (Expected from Sequence), Dog (Expected from Sequence), Mouse, Pig (Expected from Sequence), Rat (Expected from Sequence)
• Applications: Western Blot, Immunohistochemistry, ELISA
• Synonyms: FHL1, Antibody; GOAT ANTI HUMAN FHL1; anti-FHL1 antibody

• Host: Goat
• Reactivity: Bovine (Expected from Sequence), Dog (Expected from Sequence), Mouse, Pig (Expected from Sequence), Rat (Expected from Sequence)
• Clonality: Polyclonal
• Isotype: IgG
• Form/Format: Purified; Purified IgG - liquid
• Concentration: IgG concentration 0.5mg/ml. (varies by lot)
• Sequence Length: 296

• Applicable Applications for anti-FHL1 antibody: WB (Western Blot), IHC (Immunohistochemistry), ELISA
• Perservative Stabilisers: 0.02% Sodium Azide (NaN3); 0.5% Bovine Serum Albumin
• Histology Positive Control Tissue: Human testis.; Buffer Solution
• Antiserum Preparation: Antiserum to human FHL1 was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
• Target Species: Human
• Preparation and Storage: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.; Shelf Life: 18 months from date of despatch.

Application Data

(Paraffin embedded human testis stained with Goat anti human FHL1 (AAA50081))

Application Data

(Human muscle lysate probed with Goat anti human FHL1 (AAA50081))

Related Product Information for anti-FHL1 antibody

Goat anti Human FHL1 antibody recognizes human Four and a half LIM domains protein 1, also known as FHL1, Skeletal muscle LIM-protein 1 or SLIM-1. FHL1 is a 323 amino acid ~30 kDa cytoplasmic protein containing multiple LIM domains. FHL1 is abundantly expressed by skeletal muscle and has been linked with several muscular dystrophy-like muscle disorders, including Scapuloperoneal syndrome (Quinzii et al. 2008), X-linked severe early-onset reducing body myopathy (Schlessl et al. 2011), and X-linked myopathy with postural muscle atrophy (Windpassinger et al. 2008). Goat anti Human FHL1 antibody is expected to recognise FHL1 isoform 5 and isoform 2, the latter being implicated as a negative regulator of RBP J- mediated transcription (Liang et al. 2008).

NCBI and Uniprot Product Information

• NCBI GI #: 228480205
• NCBI GeneID: 2273
• NCBI Accession #: NP_001153171.1
• NCBI GenBank Nucleotide #: NM_001159699.1
• UniProt Accession #: Q13642; O95212; Q13230; Q13645; Q5JXI7; Q5M7Y6; Q6IB30; Q9NZ40; Q9UKZ8; Q9Y630; B7Z5T4; B7Z793
• Molecular Weight: 33,579 Da
• NCBI Official Full Name: four and a half LIM domains protein 1 isoform 5
• NCBI Official Synonym Full Names: four and a half LIM domains 1
• NCBI Official Symbol: FHL1
• NCBI Official Synonym Symbols: KYOT; SLIM; FHL-1; FHL1A; FHL1B; FLH1A; SLIM1; XMPMA; SLIM-1; SLIMMER
• NCBI Protein Information: four and a half LIM domains protein 1; LIM protein SLIMMER; four-and-a-half Lin11, Isl-1 and Mec-3 domains 1; skeletal muscle LIM-protein 1
• UniProt Protein Name: Four and a half LIM domains protein 1
• UniProt Gene Name: FHL1
• UniProt Synonym Gene Names: SLIM1; FHL-1; SLIM; SLIM-1
• UniProt Entry Name: FHL1_HUMAN