IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using FKBPL Polyclonal Antibody at dilution of 1:50(×200))
Rabbit FKBPL Polyclonal Antibody | anti-FKBPL antibody
FKBPL Polyclonal Antibody
Gene Names
FKBPL; NG7; DIR1; FKBP4; WISP39
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry
Purity
Antigen Affinity Purification
Synonyms
FKBPL, Antibody; FKBPL Polyclonal Antibody; DIR1; FK506 binding protein like; FK506-binding protein-like; Fkbpl; FKBPL; NG7; OTTHUMP00000029170; WAF 1/CIP1 stabilizing protein 39; WAF-1/CIP1 stabilizing protein 39; WISP39; anti-FKBPL antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Concentration
1.3mg/mL (varies by lot)
Sequence Length
349
Applicable Applications for anti-FKBPL antibody
ELISA, IHC (Immunohistochemistry)
Immunogen
Fusion protein of human FKBPL
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using FKBPL Polyclonal Antibody at dilution of 1:50(×200))
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using FKBPL Polyclonal Antibody at dilution of 1:50(×200))
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using FKBPL Polyclonal Antibody at dilution of 1:50(×200))
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using FKBPL Polyclonal Antibody at dilution of 1:50(×200))
Related Product Information for anti-FKBPL antibody
FKBPL,also named as DIR1,NG7 and WISp39,has similarity to the immunophilin protein family,which plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is thought to have a potential role in the induced radioresistance,probably by increasing the rate of DNA repair in cells exposed to X rays. Also it appears to have some involvement in general stress response in the control of the cell cycle. It regulates p21 protein stability by binding to Hsp90 and p21. Breast cancer cells stably overexpressing FKBPL became dependent on estrogen for their growth and were dramatically more sensitive to the antiestrogens tamoxifen and fulvestrant,whereas FKBPL knockdown reverses this phenotype. FKBPL is an estrogen-inducible gene that acts as a cochaperone in ERalpha/Hsp90 molecular complexes; furthermore,FKBPL levels may be both a prognostic indicator and determinant of response to endocrine therapy.
Product Categories/Family for anti-FKBPL antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
FK506-binding protein-like
NCBI Official Synonym Full Names
FKBP prolyl isomerase like
NCBI Official Symbol
FKBPL
NCBI Official Synonym Symbols
NG7; DIR1; FKBP4; WISP39
NCBI Protein Information
FK506-binding protein-like
UniProt Protein Name
FK506-binding protein-like
UniProt Gene Name
FKBPL
UniProt Synonym Gene Names
DIR1; NG7; WISp39
UniProt Entry Name
FKBPL_HUMAN
Similar Products
Product Notes
The FKBPL fkbpl (Catalog #AAA176166) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FKBPL Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's FKBPL can be used in a range of immunoassay formats including, but not limited to, ELISA, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the FKBPL fkbpl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FKBPL, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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