ICC (Immunocytochemistry)
(Immunocytochemistry of FLASH in HeLa cells with FLASH antibody at 10 ug/mL.)
Rabbit anti-Human FLASH Polyclonal Antibody | anti-FLASH antibody
FLASH Antibody
Gene Names
CASP8AP2; CED-4; FLASH; RIP25
Reactivity
Human
Applications
Immunocytochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
FLASH, Antibody; FLASH Antibody; FLASH; anti-FLASH antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
3810
Applicable Applications for anti-FLASH antibody
ICC (Immunocytochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a synthetic peptide corresponding to amino acids near the carboxy terminus of human FLASH which differ from those of mouse by one amino acid.
Target Name
FLASH
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ICC (Immunocytochemistry)
(Immunocytochemistry of FLASH in HeLa cells with FLASH antibody at 10 ug/mL.)
ICC (Immunocytochemistry)
(Immunocytochemistry of FLASH in HeLa cells with FLASH antibody at 10 ug/mL.)
WB (Western Blot)
(Western blot analysis of FLASH in HeLa whole cell lysate with FLASH antibody at 0.5 ug/mL.)
WB (Western Blot)
(Western blot analysis of FLASH in HeLa whole cell lysate with FLASH antibody at 0.5 ug/mL.)
Related Product Information for anti-FLASH antibody
A novel mammalian CED-4 homologous was recently identified and cloned in mouse and human and designated FLASH (for FLICE-associated huge protein). FLASH is involved in Fas induced apoptosis. It is recruited to Fas after the receptor cross-linking. Overexpression of wild type of FLASH facilitates and its dominant negative form inhibits Fas induced apoptosis. FLASH interacts with the DEDs of caspase-8 and FADD through the DED-like domain of FLASH and mediates activation of caspase-8. There are parallels between FLASH and Apaf-1/CED-4 although there are arguments against their structural similarity. FLASH is widely expressed.
Product Categories/Family for anti-FLASH antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
222,658 Da
NCBI Official Full Name
Homo sapiens FLASH mRNA, partial cds
NCBI Official Synonym Full Names
caspase 8 associated protein 2
NCBI Official Symbol
CASP8AP2
NCBI Official Synonym Symbols
CED-4; FLASH; RIP25
NCBI Protein Information
CASP8-associated protein 2
UniProt Protein Name
CASP8-associated protein 2
UniProt Gene Name
CASP8AP2
UniProt Entry Name
C8AP2_HUMAN
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Product Notes
The FLASH casp8ap2 (Catalog #AAA306646) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FLASH Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FLASH can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the FLASH casp8ap2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FLASH, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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