ICC (Immunocytochemistry)
(Immunocytochemistry of FOXO4 in HeLa cells with FOXO4 antibody at 10 μg/mL.)
Rabbit FOXO4 Polyclonal Antibody | anti-FOXO4 antibody
FOXO4 Antibody
Gene Names
FOXO4; AFX; AFX1; MLLT7
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunocytochemistry, Western Blot, ELISA
Purity
FOXO4 Antibody is affinity chromatography purified via peptide column.
Synonyms
FOXO4, Antibody; FOXO4 Antibody; FOXO4; AFX; AFX1; MLLT7; Forkhead box protein O4; Fork head domain transcription factor AFX1; forkhead box O4; anti-FOXO4 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
FOXO4 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
505
Applicable Applications for anti-FOXO4 antibody
IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
FOXO4 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human FOXO4.
Buffer
FOXO4 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
FOXO4 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ICC (Immunocytochemistry)
(Immunocytochemistry of FOXO4 in HeLa cells with FOXO4 antibody at 10 μg/mL.)
ICC (Immunocytochemistry)
(Immunocytochemistry of FOXO4 in HeLa cells with FOXO4 antibody at 10 μg/mL.)
WB (Western Blot)
(Western blot analysis of FOXO4 in A-20 cell lysate with FOXO4 antibody at (A) 0.5 and (B) 1 μg/mL.)
WB (Western Blot)
(Western blot analysis of FOXO4 in A-20 cell lysate with FOXO4 antibody at (A) 0.5 and (B) 1 μg/mL.)
Related Product Information for anti-FOXO4 antibody
FOXO4 Antibody: FOXO4 is a ubiquitously expressed protein member of a subfamily of the forkhead homeotic gene family of transcription factors and shuttles between the cytoplasm and nucleus. FOXO transcription factors are key players of cell fate decisions, metabolism, stress resistance, tumor suppression and are regulated by growth factors, oxidative stress or nutrient deprivation. In the absence of PI3K/AKT activation, FOXO4 localizes in the nucleus where it functions as a transcription factor. FOXO4 can also be phosphorylated by JNK following induction of reactive oxygen species (ROS), resulting in transcriptional activation and the induction of a negative feedback mechanism to counteract the ROS. It is through this mechanism that FOXO4 is thought to sensitize cancer cells to doxorubicin-mediated toxicity.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
47,941 Da
NCBI Official Full Name
forkhead box protein O4 isoform 1
NCBI Official Synonym Full Names
forkhead box O4
NCBI Official Symbol
FOXO4
NCBI Official Synonym Symbols
AFX; AFX1; MLLT7
NCBI Protein Information
forkhead box protein O4; fork head domain transcription factor AFX1; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 7
UniProt Protein Name
Forkhead box protein O4
UniProt Gene Name
FOXO4
UniProt Synonym Gene Names
AFX; AFX1; MLLT7
UniProt Entry Name
FOXO4_HUMAN
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Product Notes
The FOXO4 foxo4 (Catalog #AAA39544) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FOXO4 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's FOXO4 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the FOXO4 foxo4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FOXO4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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