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IHC (Immunohistochemistry)
(Anti- FXYZ1 Picoband antibody, AAA46254, IHC(P)IHC(P): Human Prostatic Cancer Tissue)
FXYD1 Polyclonal Antibody | anti-FXYD1 antibody
Anti-FXYD1 Antibody
Gene Names
FXYD1; PLM
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen Affinity Purified
Synonyms
FXYD1, Antibody; Anti-FXYD1 Antibody; Phospholemman; FXYD domain containing ion transport regulator 1; PLM; anti-FXYD1 antibody
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Immunogen Affinity Purified
Form/Format
Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Sequence Length
92
Applicable Applications for anti-FXYD1 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
E Coli-derived human FXYD1 recombinant protein (Position: E21-R92). Human FXYD1 shares 86.1% and 87.5% amino acid (aa) sequence identity with mouse and rat FXYD1, respectively.
Ig Type
Rabbit IgG
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquoted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohistochemistry)
(Anti- FXYZ1 Picoband antibody, AAA46254, IHC(P)IHC(P): Human Prostatic Cancer Tissue)
IHC (Immunohistochemistry)
(Anti- FXYZ1 Picoband antibody, AAA46254, IHC(P)IHC(P): Human Prostatic Cancer Tissue)
IHC (Immunohistochemisry)
(Anti- FXYZ1 Picoband antibody, AAA46254, IHC(P)IHC(P): Rat Cardiac Muscle Tissue)
IHC (Immunohistochemisry)
(Anti- FXYZ1 Picoband antibody, AAA46254, IHC(P)IHC(P): Rat Cardiac Muscle Tissue)
IHC (Immunohiostchemistry)
(Anti- FXYZ1 Picoband antibody, AAA46254, IHC(P)IHC(P): Mouse Cardiac Muscle Tissue)
IHC (Immunohiostchemistry)
(Anti- FXYZ1 Picoband antibody, AAA46254, IHC(P)IHC(P): Mouse Cardiac Muscle Tissue)
WB (Western Blot)
(Anti- FXYZ1 Picoband antibody, AAA46254, Western blottingAll lanes: Anti FXYZ1 (AAA46254) at 0.5ug/mlLane 1: Rat Liver Tissue Lysate at 50ugLane 2: Rat Cardiac Muscle Tissue Lysate at 50ugLane 3: Mouse Cardiac Muscle Tissue Lysate at 50ugLane 4: HEPG2 Whole Cell Lysate at 40ugLane 5: HELA Whole Cell Lysate at 40ugPredicted bind size: 10KDObserved bind size: 10KD)
WB (Western Blot)
(Anti- FXYZ1 Picoband antibody, AAA46254, Western blottingAll lanes: Anti FXYZ1 (AAA46254) at 0.5ug/mlLane 1: Rat Liver Tissue Lysate at 50ugLane 2: Rat Cardiac Muscle Tissue Lysate at 50ugLane 3: Mouse Cardiac Muscle Tissue Lysate at 50ugLane 4: HEPG2 Whole Cell Lysate at 40ugLane 5: HELA Whole Cell Lysate at 40ugPredicted bind size: 10KDObserved bind size: 10KD)
Related Product Information for anti-FXYD1 antibody
Description: Rabbit IgG polyclonal antibody for Phospholemman(FXYD1) detection. Tested with WB, IHC-P in Human;Rat;Mouse.
Background: Phospholemman is a protein that in humans is encoded by the FXYD1 gene. This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. The protein encoded by this gene is a plasma membrane substrate for several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. Transcript variants with different 5' UTR sequences have been described in the literature.
Background: Phospholemman is a protein that in humans is encoded by the FXYD1 gene. This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. The protein encoded by this gene is a plasma membrane substrate for several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. Transcript variants with different 5' UTR sequences have been described in the literature.
References
1. "Entrez Gene: FXYD1 FXYD domain containing ion transport regulator 1 (phospholemman)". 2. Chen LS, Lo CF, Numann R, Cuddy M (Jul 1997). "Characterization of the human and rat phospholemman (PLM) cDNAs and localization of the human PLM gene to chromosome 19q13.1". Genomics 41 (3): 435-43.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
phospholemman
NCBI Official Synonym Full Names
FXYD domain containing ion transport regulator 1
NCBI Official Symbol
FXYD1
NCBI Official Synonym Symbols
PLM
NCBI Protein Information
phospholemman
UniProt Protein Name
Phospholemman
UniProt Gene Name
FXYD1
UniProt Synonym Gene Names
PLM
UniProt Entry Name
PLM_HUMAN
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Product Notes
The FXYD1 fxyd1 (Catalog #AAA46254) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-FXYD1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's FXYD1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the FXYD1 fxyd1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FXYD1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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