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Application Data
(Dilution: IHC 1:100-200)
Rabbit GABA B Receptor 2 Polyclonal Antibody | anti-GABAB2 antibody
GABA B Receptor 2 Polyclonal Antibody
Gene Names
GABBR2; HG20; GPR51; GPRC3B; GABABR2; HRIHFB2099
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry
Synonyms
GABA B Receptor 2, Antibody; GABA B Receptor 2 Polyclonal Antibody; GABBR2; GPR51; GPRC3B; Gamma-aminobutyric acid type B receptor subunit 2; GABA-B receptor 2; GABA-B-R2; GABA-BR2; GABABR2; Gb2; G-protein coupled receptor 51; HG20; anti-GABAB2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Applicable Applications for anti-GABAB2 antibody
IHC (Immunohistochemistry)
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Application Data
(Dilution: IHC 1:100-200)
Application Data
(Dilution: IHC 1:100-200)
Application Data
(Dilution: IHC 1:100-200)
Application Data
(Dilution: IHC 1:100-200)
Application Data
(Dilution: IHC 1:100-200)
Application Data
(Dilution: IHC 1:100-200)
IHC (Immunohistochemistry)
(Dilution: IHC: 1:100-200)
IHC (Immunohistochemistry)
(Dilution: IHC: 1:100-200)
Related Product Information for anti-GABAB2 antibody
Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2 (PubMed:9872744, PubMed:15617512, PubMed:18165688, PubMed:22660477, PubMed:24305054). Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins (PubMed:10773016, PubMed:24305054). Signaling inhibits adenylate cyclase, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipid hydrolysis (PubMed:9872744, PubMed:10906333, PubMed:10773016). Plays a critical role in the fine-tuning of inhibitory synaptic transmission (PubMed:22660477). Pre-synaptic GABA receptor inhibits neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA receptor decreases neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials (PubMed:10075644, PubMed:9872744, PubMed:22660477). Not only implicated in synaptic inhibition but also in hippocampal long- term potentiation, slow wave sleep, muscle relaxation and antinociception (Probable).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
105,821 Da
NCBI Official Full Name
gamma-aminobutyric acid type B receptor subunit 2
NCBI Official Synonym Full Names
gamma-aminobutyric acid (GABA) B receptor, 2
NCBI Official Symbol
GABBR2
NCBI Official Synonym Symbols
HG20; GPR51; GPRC3B; GABABR2; HRIHFB2099
NCBI Protein Information
gamma-aminobutyric acid type B receptor subunit 2; gb2; GABA-BR2; GABA-B-R2; GABA-B receptor 2; GABA-B receptor, R2 subunit; G protein-coupled receptor 51; G-protein coupled receptor 51; gamma-aminobutyric acid B receptor 2
UniProt Protein Name
Gamma-aminobutyric acid type B receptor subunit 2
UniProt Gene Name
GABBR2
UniProt Synonym Gene Names
GPR51; GPRC3B; GABA-B receptor 2; GABA-B-R2; GABA-BR2; GABABR2; Gb2
UniProt Entry Name
GABR2_HUMAN
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Product Notes
The GABAB2 gabbr2 (Catalog #AAA293737) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GABA B Receptor 2 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GABA B Receptor 2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the GABAB2 gabbr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GABA B Receptor 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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