IHC (Immunohiostchemistry)
(GCDH Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GCDH Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit GCDH Polyclonal Antibody | anti-GCDH antibody
GCDH Antibody (C-term)
Gene Names
GCDH; GCD; ACAD5
Reactivity
Human (Predicted Reactivity: Bovine, Monkey)
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
GCDH, Antibody; GCDH Antibody (C-term); Glutaryl-CoA dehydrogenase; mitochondrial; GCD; GCDH; anti-GCDH antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Bovine, Monkey)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This GCDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-365 amino acids from the C-terminal region of human GCDH.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
336-365
Sequence Length
428
Applicable Applications for anti-GCDH antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(GCDH Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GCDH Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(GCDH Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GCDH Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(Western blot analysis of GCDH (arrow) using rabbit polyclonal GCDH Antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the GCDH gene.)
WB (Western Blot)
(Western blot analysis of GCDH (arrow) using rabbit polyclonal GCDH Antibody (C-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the GCDH gene.)
Related Product Information for anti-GCDH antibody
The protein encoded by this gene belongs to the acyl-CoA
dehydrogenase family. It catalyzes the oxidative decarboxylation of
glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway
of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses
electron transfer flavoprotein as its electron acceptor. The enzyme
exists in the mitochondrial matrix as a homotetramer of 45-kD
subunits. Alternatively spliced transcript variants encoding
different isoforms have been identified.
dehydrogenase family. It catalyzes the oxidative decarboxylation of
glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway
of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses
electron transfer flavoprotein as its electron acceptor. The enzyme
exists in the mitochondrial matrix as a homotetramer of 45-kD
subunits. Alternatively spliced transcript variants encoding
different isoforms have been identified.
Product Categories/Family for anti-GCDH antibody
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Park, J.D., et al. J. Korean Med. Sci. 25(6):957-960(2010)
Strauss, K.A., et al. Brain 133 (PT 1), 76-92 (2010) :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Ganesh, S.K., et al. Nat. Genet. 41(11):1191-1198(2009)
Park, J.D., et al. J. Korean Med. Sci. 25(6):957-960(2010)
Strauss, K.A., et al. Brain 133 (PT 1), 76-92 (2010) :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Ganesh, S.K., et al. Nat. Genet. 41(11):1191-1198(2009)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
48127
NCBI Official Full Name
glutaryl-CoA dehydrogenase, mitochondrial isoform a
NCBI Official Synonym Full Names
glutaryl-CoA dehydrogenase
NCBI Official Symbol
GCDH
NCBI Official Synonym Symbols
GCD; ACAD5
NCBI Protein Information
glutaryl-CoA dehydrogenase, mitochondrial
UniProt Protein Name
Glutaryl-CoA dehydrogenase, mitochondrial
UniProt Gene Name
GCDH
UniProt Synonym Gene Names
GCD
UniProt Entry Name
GCDH_HUMAN
Similar Products
Product Notes
The GCDH gcdh (Catalog #AAA290106) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 336-365. The GCDH Antibody (C-term) reacts with Human (Predicted Reactivity: Bovine, Monkey) and may cross-react with other species as described in the data sheet. AAA Biotech's GCDH can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the GCDH gcdh for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GCDH, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.