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product-image-AAA77634_AD15.jpg Application Data (Figure 1: Immunofluorescence staining of a 9 days old zebrafish embryo)

Rabbit GFAP (K39) Polyclonal Antibody

Rabbit anti GFAP (K39)

Reactivity
Human, Mouse, Rat, Zebrafish
Applications
Western Blot, Immunohistochemistry, Immunohistochemistry
Synonyms
GFAP (K39), Antibody; Rabbit anti GFAP (K39); anti-GFAP (K39) antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse, Rat, Zebrafish
Clonality
Polyclonal
Specificity
K39 reacts exclusively with glial fibrillary acidic protein which is present in astrocytes in the central nervous system and Schwann cells.
Form/Format
Each vial contains 100 ul Rabbit polyclonal Serum containing 0.09% sodium azide.
Applicable Applications for anti-GFAP (K39) antibody
WB (Western Blot), IHC (Immunohistochemistry), IHC (Immunohistochemistry)
Source
K39 is a Rabbit polyclonal antiSerum derived by immunization of a Rabbit with a glial fibrillary acidic protein prepaRation from Human spinal cord.
Preparation and Storage
For prolonged storage prepare appropriate aliquots and store at or below -20°C. Prior to use, an aliquot is thawed slowly in the dark at ambient temperature, spun down again and used to prepare working dilutions by adding sterile phosphate buffered saline (PBS, pH 7.2). Repeated thawing and freezing should be avoided. Working dilutions should be stored at +4°C, not refrozen, and preferably used the same day. If a slight precipitation occurs upon storage, this should be removed by centrifugation. It will not affect the performance or the concentration of the product.

Application Data

(Figure 1: Immunofluorescence staining of a 9 days old zebrafish embryo)

product-image-AAA77634_AD15.jpg Application Data (Figure 1: Immunofluorescence staining of a 9 days old zebrafish embryo)
Related Product Information for anti-GFAP (K39) antibody
GFAP (55 kD) is selectively loCated in astrocytes and represents the major constituent of astrocytic intermediate filaments. GFAP expression levels are highly variable during development of the central nervous system. In adults, GFAP levels increase as a result of the prolifeRation of astrocytes that occurs in a response to a variety of physical, chemical and etiological insults, including Alzheimer's disease, epilepsy and multiple sclerosis. In the peripheral nervous system GFAP is expressed by Schwann cells. Upon differentiation, myelin forming Schwann cells down-regulate GFAP, whereas in non-myelin forming Schwann cells GFAP persists into adulthood.
Product Categories/Family for anti-GFAP (K39) antibody
References
Ramaekers, F. C., Puts, J. J., Moesker, O., Kant, A., Huysmans, A., Haag, D., Jap, P. H., Herman, C. J., and Vooijs, G. P. (1983). Antibodies to intermediate filament proteins in the immunohistochemical identifiCation of Human tumours: an overview, Histochem J 15, 691-713. Herpers, M. J., Ramaekers, F. C., Aldeweireldt, J., Moesker, O., and Slooff, J. (1986). Co-expression of glial fibrillary acidic protein- and vimentin-type intermediate filaments in Human astrocytomas, Acta Neuropathol 70, 333-9.

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
NCBI Official Full Name
glial fibrillary acidic protein

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Product Notes

The GFAP (K39) (Catalog #AAA77634) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti GFAP (K39) reacts with Human, Mouse, Rat, Zebrafish and may cross-react with other species as described in the data sheet. AAA Biotech's GFAP (K39) can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the GFAP (K39) for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GFAP (K39), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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