FCM/FACS (Flow Cytometry)
(GGTLC2 Antibody (Center) flow cytometric analysis of U251 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Rabbit GGTLC2 Polyclonal Antibody | anti-GGTLC2 antibody
GGTLC2 Antibody (Center)
Gene Names
GGTLC2; GGTL4
Reactivity
Human (Predicted Reactivity: Mouse, Pig, Rat)
Applications
Flow Cytometry, Functional Assay, Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
GGTLC2, Antibody; GGTLC2 Antibody (Center); Gamma-glutamyltransferase light chain 2; Gamma-glutamyltransferase-like protein 4; GGTLC2; GGTL4; anti-GGTLC2 antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Mouse, Pig, Rat)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This GGTLC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-154 amino acids from the Central region of human GGTLC2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
127-154
Sequence Length
218
Applicable Applications for anti-GGTLC2 antibody
FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
FCM/FACS (Flow Cytometry)
(GGTLC2 Antibody (Center) flow cytometric analysis of U251 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
FCM/FACS (Flow Cytometry)
(GGTLC2 Antibody (Center) flow cytometric analysis of U251 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
IHC (Immunohiostchemistry)
(GGTLC2 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GGTLC2 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(GGTLC2 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the GGTLC2 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(GGTLC2 Antibody (Center) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the GGTLC2 antibody detected the GGTLC2 protein (arrow).)
WB (Western Blot)
(GGTLC2 Antibody (Center) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the GGTLC2 antibody detected the GGTLC2 protein (arrow).)
Related Product Information for anti-GGTLC2 antibody
Gamma-glutamyltransferase-1 (GGT1; MIM 612346) is a
membrane-bound extracellular enzyme that cleaves gamma-glutamyl
peptide bonds in glutathione and other peptides and transfers the
gamma-glutamyl moiety to acceptors. Autocatalytic cleavage of the
GGT1 precursor polypeptide produces a heavy chain and a light chain
that associate with each other to form the functional enzyme. Light
chain-only GGTs, such as GGTLC2, contain a region corresponding to
the GGT1 light chain, but they lack the membrane-anchoring heavy
chain region (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied
by OMIM].
membrane-bound extracellular enzyme that cleaves gamma-glutamyl
peptide bonds in glutathione and other peptides and transfers the
gamma-glutamyl moiety to acceptors. Autocatalytic cleavage of the
GGT1 precursor polypeptide produces a heavy chain and a light chain
that associate with each other to form the functional enzyme. Light
chain-only GGTs, such as GGTLC2, contain a region corresponding to
the GGT1 light chain, but they lack the membrane-anchoring heavy
chain region (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied
by OMIM].
Product Categories/Family for anti-GGTLC2 antibody
References
Heisterkamp, N., et al. Hum. Genet. 123(4):321-332(2008)
Dunham, I., et al. Nature 402(6761):489-495(1999)
Kawasaki, K., et al. Genome Res. 7(3):250-261(1997)
Leh, H., et al. FEBS Lett. 394(3):258-262(1996)
Wetmore, L.A., et al. Proc. Natl. Acad. Sci. U.S.A. 90(16):7461-7465(1993)
Dunham, I., et al. Nature 402(6761):489-495(1999)
Kawasaki, K., et al. Genome Res. 7(3):250-261(1997)
Leh, H., et al. FEBS Lett. 394(3):258-262(1996)
Wetmore, L.A., et al. Proc. Natl. Acad. Sci. U.S.A. 90(16):7461-7465(1993)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
23661
NCBI Official Full Name
gamma-glutamyltransferase light chain 2 isoform 1
NCBI Official Synonym Full Names
gamma-glutamyltransferase light chain 2
NCBI Official Symbol
GGTLC2
NCBI Official Synonym Symbols
GGTL4
NCBI Protein Information
gamma-glutamyltransferase light chain 2
UniProt Protein Name
Gamma-glutamyltransferase light chain 2
UniProt Gene Name
GGTLC2
UniProt Synonym Gene Names
GGTL4
UniProt Entry Name
GGTL2_HUMAN
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Product Notes
The GGTLC2 ggtlc2 (Catalog #AAA287611) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 127-154. The GGTLC2 Antibody (Center) reacts with Human (Predicted Reactivity: Mouse, Pig, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's GGTLC2 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the GGTLC2 ggtlc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GGTLC2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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