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WB (Western Blot)
(Western Blot of 20 ug of human brain lysate showing specific immunolabeling of mGluR1.)
Rabbit GluR1 Polyclonal Antibody | anti-GRIA1 antibody
Anti-GluR1 Antibody
Gene Names
GRM1; MGLU1; GPRC1A; MGLUR1; SCAR13; PPP1R85
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Synonyms
GluR1, Antibody; Anti-GluR1 Antibody; GRIA1; Glutamate receptor 1; AMPA-selective glutamate receptor 1; Glutamate receptor ionotropic; AMPA 1; GluR-K1; GluR-A; GLUH1; mGluR1; anti-GRIA1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Reacts with internal residues of the human, rat and mouse GluR1 alpha protein.
Form/Format
Liquid; Antigen Affinity Purified; PBS + 0.02% NaN3
Applicable Applications for anti-GRIA1 antibody
WB (Western Blot)
Immunogen Species
Human
Immunogen
Synthetic peptide corresponding to amino acids from an internal region of the human GluR1 alpha protein
Country of Origin
United States
Preparation and Storage
Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20 degree C or -80 degree C, while keeping a working aliquot stored at 4 degree C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
After date of receipt, stable for at least 1 year at -20 degree C.
After date of receipt, stable for at least 1 year at -20 degree C.
WB (Western Blot)
(Western Blot of 20 ug of human brain lysate showing specific immunolabeling of mGluR1.)
WB (Western Blot)
(Western Blot of 20 ug of human brain lysate showing specific immunolabeling of mGluR1.)
IHC (Immunohistochemisry)
(Immunohistochemistry of mGluR and 5-HTR subtypes in dLGN of Galpha11-/- mice. mGluR1alpha-specific antibodies caused strong staining as in the dLGN of Galphaq/Galpha11-/-mice. Scale bars indicate 100 um. Image from the following publication (http://journal.frontiersin.org/article/10.3389/fncel.2010.00132/abstract) licensed under a CC-BY license.)
IHC (Immunohistochemisry)
(Immunohistochemistry of mGluR and 5-HTR subtypes in dLGN of Galpha11-/- mice. mGluR1alpha-specific antibodies caused strong staining as in the dLGN of Galphaq/Galpha11-/-mice. Scale bars indicate 100 um. Image from the following publication (http://journal.frontiersin.org/article/10.3389/fncel.2010.00132/abstract) licensed under a CC-BY license.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of rat brain frozen sections (cingulate cortex) showing specific staining of mGluR1 in red. DAPI was used to counterstain cell nuclei (blue).)
IHC (Immunohiostchemistry)
(Immunohistochemistry of rat brain frozen sections (cingulate cortex) showing specific staining of mGluR1 in red. DAPI was used to counterstain cell nuclei (blue).)
ICC (Immunocytochemistry)
(Immunocytochemistry of primary rat cortical neurons showing specific staining of mGluR1.)
ICC (Immunocytochemistry)
(Immunocytochemistry of primary rat cortical neurons showing specific staining of mGluR1.)
Related Product Information for anti-GRIA1 antibody
mGluR1 rabbit polyclonal primary antibody from the lab is produced in-house. It detects human, mouse, and rat mGluR1 and is antigen affinity purified. It is great for use in WB.
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. The Glutamate Receptor, Metabotropic, 1, (mGluR1 alpha) activates phospholipase C and participates in the central action of glutamate in the central nervous system, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. The Glutamate Receptor, Metabotropic, 1, (mGluR1 alpha) activates phospholipase C and participates in the central action of glutamate in the central nervous system, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum
Product Categories/Family for anti-GRIA1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
1194
NCBI Official Full Name
Metabotropic glutamate receptor 1
NCBI Official Synonym Full Names
glutamate receptor, metabotropic 1
NCBI Official Symbol
GRM1
NCBI Official Synonym Symbols
MGLU1; GPRC1A; MGLUR1; SCAR13; PPP1R85
NCBI Protein Information
metabotropic glutamate receptor 1; protein phosphatase 1, regulatory subunit 85
UniProt Protein Name
Metabotropic glutamate receptor 1
UniProt Gene Name
GRM1
UniProt Synonym Gene Names
GPRC1A; MGLUR1; mGluR1
UniProt Entry Name
GRM1_HUMAN
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Product Notes
The GRIA1 grm1 (Catalog #AAA72778) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-GluR1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GluR1 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the GRIA1 grm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GluR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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