WB (Western Blot)
(Western Blot analysis of K562 cells using Glut1 Polyclonal Antibody diluted at 1:500.)
Rabbit Glut1 Polyclonal Antibody | anti-Glut1 antibody
Glut1 Rabbit pAb
Gene Names
SLC2A1; PED; DYT9; GLUT; DYT17; DYT18; EIG12; GLUT1; HTLVR; GLUT1DS
Reactivity
Human, Mouse, Rat
Applications
ELISA, Flow Cytometry, Functional Assay, Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Affinity purified
Synonyms
Glut1, Antibody; Glut1 Rabbit pAb; CSE; PED; DYT9; GLUT; DYT17; DYT18; EIG12; GLUT1; HTLVR; GLUT-1; SDCHCN; GLUT1DS; anti-Glut1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Glut1 Polyclonal Antibody detects endogenous levels of Glut1 protein.
Purity/Purification
Affinity purified
Form/Format
Supplied in 50nM Tris-Glycine (pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Concentration
1 mg/ml (varies by lot)
Applicable Applications for anti-Glut1 antibody
ELISA, FCM/FACS (Flow Cytometry), IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
The antiserum was produced against synthesized peptide derived from human GLUT1. AA range: 441-490.
Preparation and Storage
Store at -15 degree C to -25 degree C (not lower than -25 degree C).
WB (Western Blot)
(Western Blot analysis of K562 cells using Glut1 Polyclonal Antibody diluted at 1:500.)
WB (Western Blot)
(Western Blot analysis of K562 cells using Glut1 Polyclonal Antibody diluted at 1:500.)
IF (Immunofluorescence)
(Immunofluorescence analysis of A549. 1,primary Antibody (red) was diluted at 1:200 (4 degree C overnight). 2, Goat Anti Rabbit IgG (H&L) - Alexa Fluor 594. Secondary antibody was diluted at 1:1000 (room temperature, 50min). 3, Picture B: DAPI (blue) 10min.)
IF (Immunofluorescence)
(Immunofluorescence analysis of A549. 1,primary Antibody (red) was diluted at 1:200 (4 degree C overnight). 2, Goat Anti Rabbit IgG (H&L) - Alexa Fluor 594. Secondary antibody was diluted at 1:1000 (room temperature, 50min). 3, Picture B: DAPI (blue) 10min.)
Related Product Information for anti-Glut1 antibody
Cellular Localization: Cell membrane ; Multi-pass membrane protein . Melanosome . Photoreceptor inner segment. Localizes primarily at the cell surface (PubMed:18245775, PubMed:19449892, PubMed: 23219802, PubMed:25982116, PubMed:24847886). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065).
Tissue Specificity: Detected in erythrocytes (at protein level). Expressed at variable levels in many human tissues.
Function: Disease: Defects in SLC2A1 are the cause of autosomal dominant GLUT1 deficiency syndrome [MIM:606777]; also called blood-brain barrier glucose transport defect. This disease causes a defect in glucose transport across the blood-brain barrier. It is characterized by infantile seizures, delayed development, and acquired microcephaly.,Disease:Defects in SLC2A1 are the cause of dystonia type 18 (DYT18) [MIM:612126]. DYT18 is an exercise-induced paroxysmal dystonia/dyskinesia. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. DYT18 is characterized by attacks of involuntary movements triggered by certain stimuli such as sudden movement or prolonged exercise. In some patients involuntary exertion-induced dystonic, choreoathetotic, and ballistic movements may be associated with macrocytic hemolytic anemia.,Function:Facilitative glucose transporter. This isoform may be responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses.,online information:GLUT1 entry,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.,subcellular location:Localizes primarily at the cell surface (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,tissue specificity:Expressed at variable levels in many human tissues.
Tissue Specificity: Detected in erythrocytes (at protein level). Expressed at variable levels in many human tissues.
Function: Disease: Defects in SLC2A1 are the cause of autosomal dominant GLUT1 deficiency syndrome [MIM:606777]; also called blood-brain barrier glucose transport defect. This disease causes a defect in glucose transport across the blood-brain barrier. It is characterized by infantile seizures, delayed development, and acquired microcephaly.,Disease:Defects in SLC2A1 are the cause of dystonia type 18 (DYT18) [MIM:612126]. DYT18 is an exercise-induced paroxysmal dystonia/dyskinesia. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. DYT18 is characterized by attacks of involuntary movements triggered by certain stimuli such as sudden movement or prolonged exercise. In some patients involuntary exertion-induced dystonic, choreoathetotic, and ballistic movements may be associated with macrocytic hemolytic anemia.,Function:Facilitative glucose transporter. This isoform may be responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses.,online information:GLUT1 entry,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.,subcellular location:Localizes primarily at the cell surface (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,tissue specificity:Expressed at variable levels in many human tissues.
Product Categories/Family for anti-Glut1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
55 kD (Observed)
NCBI Official Full Name
solute carrier family 2, facilitated glucose transporter member 1
NCBI Official Synonym Full Names
solute carrier family 2 (facilitated glucose transporter), member 1
NCBI Official Symbol
SLC2A1
NCBI Official Synonym Symbols
PED; DYT9; GLUT; DYT17; DYT18; EIG12; GLUT1; HTLVR; GLUT1DS
NCBI Protein Information
solute carrier family 2, facilitated glucose transporter member 1; GLUT-1; hepG2 glucose transporter; glucose transporter type 1, erythrocyte/brain; human T-cell leukemia virus (I and II) receptor
UniProt Protein Name
Solute carrier family 2, facilitated glucose transporter member 1
UniProt Gene Name
SLC2A1
UniProt Synonym Gene Names
GLUT1; GLUT-1
UniProt Entry Name
GTR1_HUMAN
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Product Notes
The Glut1 slc2a1 (Catalog #AAA268952) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Glut1 Rabbit pAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Glut1 can be used in a range of immunoassay formats including, but not limited to, ELISA, FCM/FACS (Flow Cytometry), IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the Glut1 slc2a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Glut1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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