Rabbit GLUT10 Polyclonal Antibody | anti-SLC2A10 antibody
Anti-GLUT10 Antibody
After date of receipt, stable for at least 1 year at -20 degree C.
WB (Western Blot)
(Western Blot of NCI-H1299 non-small cell lung tumor cells transfected with the eukaryotic expression vectors pcDNA3.1/V5 (lanes 1,2), pCMV-GLUT10 (lanes 3,4), and pCMV-GLUT1 (lanes 5,6) showing specific immunolabeling of GLUT10.)
WB (Western Blot)
(Western Blot showing specific immunolabeling of GLUT10 in Lane 1: 10ug of protein from liver Lane 2: 10ug of protein from cochlea (E18) Lane 3: 10ug of protein from cochlea (P7) Lane 4: 10ug of protein from cochlea (P10) Lane 5: 10ug of protein from cochlea (P14) Lane 6: 10ug of protein from cochlea (P17) Lane 7: 10ug of protein from cochlea (P60) Lane 8: 10ug of protein from cochlea (1 Year).)
IHC (Immunohistochemistry)
(Immunohistochemistry of mouse inner ear frozen sections showing specific staining of GLUT10 at 1:200 dilution. Sections were incubated with secondary (anti-rabbit Cy3, 1:400) RT 1 hr. Slides mounted with fluoromont G and examined under a confocal microscope. Strong immunoreactivity (red) is observed in the inner and outer hair cells and basilar membrane. Spiral ganglion neurons display moderate staining.)
Non-insulin-dependent diabetes mellitus (NIDDM) is a multifactoral disease with both environmental and genetics causes. Genome-wide screening procedures have identified several susceptibility loci for NIDDM within the human genome. A putative sugar transporter that has been localized to human chromosome 20q12-q13.1, one of the genomic loci associated with NIDDM. Because of the strong resemblance of this novel protein to members of the mammalian facilitative glucose transporter family (GLUT), the protein is known as GLUT10 (HGMW-approved gene symbol SLC2A10). Data suggests that GLUT10 an excellent candidate for a susceptibility gene involved in NIDDM. In addition, mouse whole genome microarray data shows GLUT1 and GLUT10 have the highest expression of the GLUT10 family in mouse cochlea. Ito et al showed vascular endothelial cells, basal cell layer of the stria vascularis and satellite cells contained GLUT1. However, this is the first report that GluT10 exists in the mouse cochlea. Current studies are investigating the location of GLUT10 expression in the mouse, rat, GP and monkey cochlea.
NCBI and Uniprot Product Information
Similar Products
Product Notes
The SLC2A10 slc2a10 (Catalog #AAA72772) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-GLUT10 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GLUT10 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the SLC2A10 slc2a10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GLUT10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
