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product-image-AAA46026_WB13.jpg WB (Western Blot) (Anti- GAD67 Picoband antibody, AAA46026, Western blottingAll lanes: Anti GAD67 (AAA46026) at 0.5ug/mlLane 1: Rat Testis Tissue Lysate at 50ugLane 2: Mouse Brain Tissue Lysate at 50ugLane 3: MCF-7 Whole Cell Lysate at 40ugPredicted bind size: 67KDObserved bind size: 67KD)

Rabbit Glutamate decarboxylase 1 Polyclonal Antibody | anti-GAD1 antibody

Anti-GAD67 Antibody

Gene Names
GAD1; GAD; SCP; CPSQ1
Reactivity
Human, Rat. No cross reactivity with other proteins.
Applications
Western Blot
Purity
Immunogen affinity purified.
Synonyms
Glutamate decarboxylase 1, Antibody; Anti-GAD67 Antibody; 67 kDa glutamic acid decarboxylase antibody; DCE1 antibody; DCE1_HUMAN antibody; EC 4.1.1.15 antibody; FLJ45882 antibody; GAD 1 antibody; GAD 67 antibody; GAD antibody; GAD-67 antibody; GAD1 antibody; Glutamate decarboxylase 1 (brain 67kD) antibody; Glutamate decarboxylase 1 antibody; Glutamate decarboxylase 1 brain 67kD antibody; Glutamate decarboxylase 1 brain 67kDa antibody; Glutamate decarboxylase 67 kDa isoform antibody; OTTHUMP00000041055 antibody; SCP antibody; glutamate decarboxylase 1 (brain, 67kDa); anti-GAD1 antibody
Ordering
Host
Rabbit
Reactivity
Human, Rat. No cross reactivity with other proteins.
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Sequence Length
594
Applicable Applications for anti-GAD1 antibody
WB (Western Blot)
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Immunogen
E.coli-derived human GAD67 recombinant protein (Position: N14-D122). Human GAD67 shares 95% amino acid (aa) sequence identity with both mouse and rat GAD67.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

WB (Western Blot)

(Anti- GAD67 Picoband antibody, AAA46026, Western blottingAll lanes: Anti GAD67 (AAA46026) at 0.5ug/mlLane 1: Rat Testis Tissue Lysate at 50ugLane 2: Mouse Brain Tissue Lysate at 50ugLane 3: MCF-7 Whole Cell Lysate at 40ugPredicted bind size: 67KDObserved bind size: 67KD)

product-image-AAA46026_WB13.jpg WB (Western Blot) (Anti- GAD67 Picoband antibody, AAA46026, Western blottingAll lanes: Anti GAD67 (AAA46026) at 0.5ug/mlLane 1: Rat Testis Tissue Lysate at 50ugLane 2: Mouse Brain Tissue Lysate at 50ugLane 3: MCF-7 Whole Cell Lysate at 40ugPredicted bind size: 67KDObserved bind size: 67KD)

WB (Western Blot)

(Anti- GAD67 Picoband antibody, AAA46026, Western blottingAll lanes: Anti GAD67 (AAA46026) at 0.5ug/mlWB: Recombinant Human GAD67 Protein 0.5ngPredicted bind size: 39KDObserved bind size: 39KD)

product-image-AAA46026_WB15.jpg WB (Western Blot) (Anti- GAD67 Picoband antibody, AAA46026, Western blottingAll lanes: Anti GAD67 (AAA46026) at 0.5ug/mlWB: Recombinant Human GAD67 Protein 0.5ngPredicted bind size: 39KDObserved bind size: 39KD)
Related Product Information for anti-GAD1 antibody
Description: Rabbit IgG polyclonal antibody for Glutamate decarboxylase 1(GAD1) detection. Tested with WB in Human;Rat.
Background: Glutamate decarboxylase 1 (brain, 67kDa) (GAD67), also known as GAD1, is a human gene. It is mapped to 2q31.1. This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
47,440 Da
NCBI Official Full Name
glutamate decarboxylase 1 isoform GAD67
NCBI Official Synonym Full Names
glutamate decarboxylase 1 (brain, 67kDa)
NCBI Official Symbol
GAD1
NCBI Official Synonym Symbols
GAD; SCP; CPSQ1
NCBI Protein Information
glutamate decarboxylase 1; GAD-67; 67 kDa glutamic acid decarboxylase; glutamate decarboxylase 67 kDa isoform
UniProt Protein Name
Glutamate decarboxylase 1
UniProt Gene Name
GAD1
UniProt Synonym Gene Names
GAD; GAD67; GAD-67
UniProt Entry Name
DCE1_HUMAN

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Product Notes

The GAD1 gad1 (Catalog #AAA46026) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-GAD67 Antibody reacts with Human, Rat. No cross reactivity with other proteins. and may cross-react with other species as described in the data sheet. AAA Biotech's Glutamate decarboxylase 1 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the GAD1 gad1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Glutamate decarboxylase 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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