IHC (Immunohiostchemistry)
(Anti-Glutaredoxin 2 antibody, AAA45378, IHC(P)IHC(P): Rat Brain Tissue)
Rabbit Glutaredoxin 2 Polyclonal Antibody | anti-GLRX2 antibody
Anti-Glutaredoxin 2 antibody
Gene Names
GLRX2; GRX2; CGI-133
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
Glutaredoxin 2, Antibody; Anti-Glutaredoxin 2 antibody; Glutaredoxin-2, mitochondrial; glutaredoxin 2; bA101E13.1(GRX2 glutaredoxin(thioltransferase) 2) antibody; bA101E13.1 antibody; CGI133 antibody; Glrx2 antibody; GLRX2_HUMAN antibody; Glutaredoxin-2 antibody; Glutaredoxin-2, mitochondrial antibody; GRX2 antibody; mitochondrial antibody; anti-GLRX2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
164
Applicable Applications for anti-GLRX2 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human Glutaredoxin 2 (103-119aa EYGNQFQDALYKMTGER), different from the related rat sequence by two amino acids, and from the related mouse sequence by one amino acid.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.
Avoid repeated freezing and thawing.
Avoid repeated freezing and thawing.
IHC (Immunohiostchemistry)
(Anti-Glutaredoxin 2 antibody, AAA45378, IHC(P)IHC(P): Rat Brain Tissue)
IHC (Immunohiostchemistry)
(Anti-Glutaredoxin 2 antibody, AAA45378, IHC(P)IHC(P): Rat Brain Tissue)
WB (Western Blot)
(Anti-Glutaredoxin 2 antibody, AAA45378, Western blottingLane 1: Rat Testis Tissue LysateLane 2: HELA Cell LysateLane 3: U87 Cell LysateLane 4: NEU Cell LysateLane 5: JURKAT Cell LysateLane 6: MCF-7 Cell Lysate)
WB (Western Blot)
(Anti-Glutaredoxin 2 antibody, AAA45378, Western blottingLane 1: Rat Testis Tissue LysateLane 2: HELA Cell LysateLane 3: U87 Cell LysateLane 4: NEU Cell LysateLane 5: JURKAT Cell LysateLane 6: MCF-7 Cell Lysate)
Related Product Information for anti-GLRX2 antibody
Description: Rabbit IgG polyclonal antibody for Glutaredoxin-2, mitochondrial(GLRX2) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
Background: GLRX2(Glutaredoxin-2) also known as Glutaredoxin-2, mitochondrial or GRX2, is a protein that in humans is encoded by the GLRX2 gene. Glutaredoxins(e.g., GLRX) are a family of glutathione-dependent hydrogen donors that participate in a variety of cellular redox reactions. By sequence analysis, Lundberg et al.(2001) and Gladyshev et al.(2001) identified the GLRX2 gene within a clone mapping to chromosome 1q31.2-q31.3. Lundberg et al.(2001) determined that the GLRX2 gene contains 5 exons spanning about 9.6 kb. The GLRX2B transcript uses a first exon(exon 1B) located upstream from the first exon used by the GLRX2A transcript(exon 1A), suggesting that alternative splicing generates the isoforms. Lundberg et al.(2001)assayed reductase activity in recombinant proteins of both GLRX2 isoforms. They found that both have GSH-dependent dehydroascorbate reductase activity and 2-hydroxyethyl disulfide reductase activity.
Background: GLRX2(Glutaredoxin-2) also known as Glutaredoxin-2, mitochondrial or GRX2, is a protein that in humans is encoded by the GLRX2 gene. Glutaredoxins(e.g., GLRX) are a family of glutathione-dependent hydrogen donors that participate in a variety of cellular redox reactions. By sequence analysis, Lundberg et al.(2001) and Gladyshev et al.(2001) identified the GLRX2 gene within a clone mapping to chromosome 1q31.2-q31.3. Lundberg et al.(2001) determined that the GLRX2 gene contains 5 exons spanning about 9.6 kb. The GLRX2B transcript uses a first exon(exon 1B) located upstream from the first exon used by the GLRX2A transcript(exon 1A), suggesting that alternative splicing generates the isoforms. Lundberg et al.(2001)assayed reductase activity in recombinant proteins of both GLRX2 isoforms. They found that both have GSH-dependent dehydroascorbate reductase activity and 2-hydroxyethyl disulfide reductase activity.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
18,726 Da
NCBI Official Full Name
Glutaredoxin-2, mitochondrial
NCBI Official Synonym Full Names
glutaredoxin 2
NCBI Official Symbol
GLRX2
NCBI Official Synonym Symbols
GRX2; CGI-133
NCBI Protein Information
glutaredoxin 2; bA101E13.1 (GRX2 glutaredoxin (thioltransferase) 2)
UniProt Protein Name
Glutaredoxin-2, mitochondrial
UniProt Gene Name
GLRX2
UniProt Synonym Gene Names
GRX2
UniProt Entry Name
GLRX2_HUMAN
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Product Notes
The GLRX2 glrx2 (Catalog #AAA45378) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Glutaredoxin 2 antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Glutaredoxin 2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the GLRX2 glrx2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Glutaredoxin 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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