IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human liver cancer tissue, using GNA11 antibody.)
Rabbit GNA11 Polyclonal Antibody | anti-GNA11 antibody
GNA11 antibody
Gene Names
GNA11; FBH; FBH2; FHH2; HHC2; GNA-11; HYPOC2
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Antibodies were purified by affinity purification using immunogen.
Synonyms
GNA11, Antibody; GNA11 antibody; GNA-11; anti-GNA11 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total GNA11 antibody.
Purity/Purification
Antibodies were purified by affinity purification using immunogen.
Form/Format
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
359
Applicable Applications for anti-GNA11 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Type
Recombinant Protein
Immunogen Description
Recombinant protein of human GNA11.
Target Name
GNA11
Preparation and Storage
Store at -20 degree C
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human liver cancer tissue, using GNA11 antibody.)
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human liver cancer tissue, using GNA11 antibody.)
WB (Western Blot)
(Western blot analysis of extracts of various cell lines, using GNA11 antibody.)
WB (Western Blot)
(Western blot analysis of extracts of various cell lines, using GNA11 antibody.)
Related Product Information for anti-GNA11 antibody
Heterotrimeric guanine nucleotide-binding proteins (G proteins) consist of a, b and g subunits and mediate the effects of hormones, neurotransmitters, chemokines and sensory stimuli. To date, over 20 known Ga subunits have been classified into four families, Ga(s), Ga(i/o), Ga(q) and Ga(12), based on structural and functional similarities (1,2). Phosphorylation of Tyr356 of Ga(q)/Ga(11) is essential for activation of the G protein, since phenylalanine substitution for Tyr356 changes the interaction of Ga with receptors and abolishes ligand-induced IP3 formation (3).
Product Categories/Family for anti-GNA11 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
42,123 Da
NCBI Official Full Name
guanine nucleotide-binding protein subunit alpha-11
NCBI Official Synonym Full Names
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
NCBI Official Symbol
GNA11
NCBI Official Synonym Symbols
FBH; FBH2; FHH2; HHC2; GNA-11; HYPOC2
NCBI Protein Information
guanine nucleotide-binding protein subunit alpha-11
UniProt Protein Name
Guanine nucleotide-binding protein subunit alpha-11
UniProt Gene Name
GNA11
UniProt Synonym Gene Names
GA11; G alpha-11; G-protein subunit alpha-11
UniProt Entry Name
GNA11_HUMAN
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Product Notes
The GNA11 gna11 (Catalog #AAA301629) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GNA11 antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GNA11 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the GNA11 gna11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GNA11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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