Rabbit anti-Human, mouse GPX3 Polyclonal Antibody | anti-GPX3 antibody

GPX3 Antibody (Center)

Cat. Num. AAA286760

• Gene Names: GPX3; GPx-P; GSHPx-3; GSHPx-P
• Reactivity: Human, mouse
• Applications: Immunohistochemistry, ELISA, Western Blot
• Purity: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
• Synonyms: GPX3, Antibody; GPX3 Antibody (Center); Glutathione peroxidase 3; GPx-3; GSHPx-3; Extracellular glutathione peroxidase; Plasma glutathione peroxidase; GPx-P; GSHPx-P; GPX3; GPXP; anti-GPX3 antibody

• Host: Rabbit
• Reactivity: Human, mouse
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Specificity: This GPX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-123 amino acids from the Central region of human GPX3.
• Purity/Purification: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
• Form/Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Concentration: Vial Concentration: 0.4 (varies by lot)
• Sequence Positions: 93-123
• Sequence Length: 226

• Applicable Applications for anti-GPX3 antibody: IHC (Immunohistochemistry), ELISA, WB (Western Blot)
• Antigen Type: Synthetic Peptide
• Crown Antibody: Yes
• Antigen Source: HUMAN
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

IHC (Immunohiostchemistry)

(GPX3 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GPX3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)

WB (Western Blot)

(GPX3 Antibody (Center) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the GPX3 antibody detected the GPX3 protein (arrow).)

Related Product Information for anti-GPX3 antibody

This gene product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal.

Product Categories/Family for anti-GPX3 antibody

Crown Antibodies; Cancer; Cell Biology; Metabolism; Signal Transduction

References

Wang, J.Y., et al. Clin. Chim. Acta 411 (19-20), 1432-1436 (2010) : Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Fullerton, J.M., et al. Bipolar Disord 12(5):550-556(2010) Wang, Y., et al. J. Hum. Genet. 55(8):490-494(2010) Mistry, H.D., et al. Placenta 31(5):401-408(2010)

NCBI and Uniprot Product Information

• NCBI GI #: 6006001
• NCBI GeneID: 2878
• NCBI Accession #: NP_002075.2
• NCBI GenBank Nucleotide #: NM_002084.3
• UniProt Accession #: P22352; O43787; Q86W78; Q9NZ74; Q9UEL1
• Molecular Weight: 25552
• NCBI Official Full Name: glutathione peroxidase 3
• NCBI Official Synonym Full Names: glutathione peroxidase 3
• NCBI Official Symbol: GPX3
• NCBI Official Synonym Symbols: GPx-P; GSHPx-3; GSHPx-P
• NCBI Protein Information: glutathione peroxidase 3
• UniProt Protein Name: Glutathione peroxidase 3
• UniProt Gene Name: GPX3
• UniProt Synonym Gene Names: GPXP; GPx-3; GSHPx-3; GPx-P; GSHPx-P
• UniProt Entry Name: GPX3_HUMAN