IF (Immunofluorescence)
(Immunofluorescence of GRB10 in rat brain cells with GRB10 antibody at 20 μg/mL.)
Rabbit GRB10 Polyclonal Antibody | anti-GRB10 antibody
GRB10 Antibody
Gene Names
GRB10; RSS; IRBP; MEG1; GRB-IR; Grb-10
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Western Blot, ELISA
Purity
GRB10 Antibody is affinity chromatography purified via peptide column.
Synonyms
GRB10, Antibody; GRB10 Antibody; GRB10; RSS; IRBP; MEG1; GRB-IR; Grb-10; GRBIR; KIAA0207; Growth factor receptor-bound protein 10; GRB10 adapter protein; growth factor receptor-bound protein 10; anti-GRB10 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
At least three isoforms of GRB10 are known to exist; this antibody will detect all three isoforms.
Purity/Purification
GRB10 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
594
Applicable Applications for anti-GRB10 antibody
IF (Immunofluorescence), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
GRB10 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human GRB10.
Buffer
GRB10 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
GRB10 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IF (Immunofluorescence)
(Immunofluorescence of GRB10 in rat brain cells with GRB10 antibody at 20 μg/mL.)
IF (Immunofluorescence)
(Immunofluorescence of GRB10 in rat brain cells with GRB10 antibody at 20 μg/mL.)
WB (Western Blot)
(Western blot analysis of GRB10 in SK-N-SH cell lysate with GRB10 antibody at (A) 1 and (B) 2 μg/mL.)
WB (Western Blot)
(Western blot analysis of GRB10 in SK-N-SH cell lysate with GRB10 antibody at (A) 1 and (B) 2 μg/mL.)
Related Product Information for anti-GRB10 antibody
GRB10 Antibody: GRB10 belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules and function in diverse cellular processes. GRB10 is a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of GRB10 inhibits tyrosine kinase activity and results in growth suppression. GRB10 can also interact with the L isoform of the proapoptotic protein Bim. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
66,487 Da
NCBI Official Full Name
growth factor receptor-bound protein 10 isoform a
NCBI Official Synonym Full Names
growth factor receptor-bound protein 10
NCBI Official Symbol
GRB10
NCBI Official Synonym Symbols
RSS; IRBP; MEG1; GRB-IR; Grb-10
NCBI Protein Information
growth factor receptor-bound protein 10; GRB10 adapter protein; GRB10 adaptor protein; maternally expressed gene 1; insulin receptor-binding protein Grb-IR
UniProt Protein Name
Growth factor receptor-bound protein 10
UniProt Gene Name
GRB10
UniProt Synonym Gene Names
GRBIR; KIAA0207
UniProt Entry Name
GRB10_HUMAN
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Product Notes
The GRB10 grb10 (Catalog #AAA39697) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GRB10 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GRB10 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the GRB10 grb10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GRB10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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