IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human small intestinal carcinoma tissue. 1, primary Antibody was diluted at 1:200 (4°C overnight). 2, Sodium citrate pH 6.0 was used for antigen retrieval (>98°C,20 min).3, Secondary antibody was diluted at 1:200.)
Rabbit GRB14 Polyclonal Antibody | anti-GRB14 antibody
GRB14 Rabbit pAb
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Affinity Purified
Synonyms
GRB14, Antibody; GRB14 Rabbit pAb; anti-GRB14 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
GRB14 Polyclonal Antibody detects endogenous levels of GRB14 protein.
Purity/Purification
Affinity Purified
Form/Format
Liquid in PBS, pH 7.4, containing 40% glycerol, 0.05% sodium azide.
Sequence Length
540
Applicable Applications for anti-GRB14 antibody
ELISA, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Fusion protein of human GRB14
Organism
Human, Mouse, Rat
Cellular Localization
Cytoplasm. Endosome membrane; Peripheral membrane protein. Upon insulin stimulation, translocates to the plasma membrane.
Tissue specificity
Expressed at high levels in the liver, kidney, pancreas, testis, ovary, heart and skeletal muscle.
Function
Function: Interacts with the cytoplasmic domain of the autophosphorylated insulin receptor which is then inhibited. The interaction is mediated by the SH2 domain. PTM: Phosphorylated on serine residues., similarity: Belongs to the GRB7/10/14 family.
Preparation and Storage
Store at -15 to -25 degree C.
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human small intestinal carcinoma tissue. 1, primary Antibody was diluted at 1:200 (4°C overnight). 2, Sodium citrate pH 6.0 was used for antigen retrieval (>98°C,20 min).3, Secondary antibody was diluted at 1:200.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded human small intestinal carcinoma tissue. 1, primary Antibody was diluted at 1:200 (4°C overnight). 2, Sodium citrate pH 6.0 was used for antigen retrieval (>98°C,20 min).3, Secondary antibody was diluted at 1:200.)
WB (Western Blot)
(Western Blot analysis of HuvEc cells using GRB14 Polyclonal Antibody)
WB (Western Blot)
(Western Blot analysis of HuvEc cells using GRB14 Polyclonal Antibody)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
61kDa
NCBI Official Full Name
growth factor receptor-bound protein 14 isoform 1
NCBI Official Synonym Full Names
growth factor receptor bound protein 14
NCBI Official Symbol
GRB14
NCBI Protein Information
growth factor receptor-bound protein 14
UniProt Protein Name
Growth factor receptor-bound protein 14
UniProt Gene Name
GRB14
UniProt Entry Name
GRB14_HUMAN
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Product Notes
The GRB14 grb14 (Catalog #AAA268690) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GRB14 Rabbit pAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GRB14 can be used in a range of immunoassay formats including, but not limited to, ELISA, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the GRB14 grb14 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GRB14, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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