IHC (Immunohistochemisry)
(GRIA4 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GRIA4 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit GRIA4 Polyclonal Antibody | anti-GRIA4 antibody
GRIA4 Antibody (Center)
Gene Names
GRIA4; GLUR4; GLURD; GluA4; GLUR4C
Reactivity
Human, mouse (Predicted Reactivity: Monkey, Rat)
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
GRIA4, Antibody; GRIA4 Antibody (Center); Glutamate receptor 4; GluR-4; GluR4; AMPA-selective glutamate receptor 4; GluR-D; Glutamate receptor ionotropic; AMPA 4; GluA4; GRIA4; GLUR4; anti-GRIA4 antibody
Host
Rabbit
Reactivity
Human, mouse (Predicted Reactivity: Monkey, Rat)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This GRIA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-325 amino acids from the Central region of human GRIA4.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.41 (varies by lot)
Sequence Positions
296-325
Sequence Length
433
Applicable Applications for anti-GRIA4 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohistochemisry)
(GRIA4 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GRIA4 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohistochemisry)
(GRIA4 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GRIA4 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(GRIA4 Antibody (Center) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the GRIA4 antibody detected the GRIA4 protein (arrow).)
WB (Western Blot)
(GRIA4 Antibody (Center) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the GRIA4 antibody detected the GRIA4 protein (arrow).)
WB (Western Blot)
(GRIA4 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the GRIA4 antibody detected the GRIA4 protein (arrow).)
WB (Western Blot)
(GRIA4 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the GRIA4 antibody detected the GRIA4 protein (arrow).)
Related Product Information for anti-GRIA4 antibody
Glutamate receptors are the predominant excitatory
neurotransmitter receptors in the mammalian brain and are activated
in a variety of normal neurophysiologic processes. These receptors
are heteromeric protein complexes composed of multiple subunits,
arranged to form ligand-gated ion channels. The classification of
glutamate receptors is based on their activation by different
pharmacologic agonists. The subunit encoded by this gene belongs to
a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole
propionate)-sensitive glutamate receptors, and is subject to RNA
editing (AGA->GGA; R->G). Alternative splicing of this gene results
in transcript variants encoding different isoforms, which may vary
in their signal transduction properties. Some haplotypes of this
gene show a positive association with schizophrenia. [provided by
RefSeq].
neurotransmitter receptors in the mammalian brain and are activated
in a variety of normal neurophysiologic processes. These receptors
are heteromeric protein complexes composed of multiple subunits,
arranged to form ligand-gated ion channels. The classification of
glutamate receptors is based on their activation by different
pharmacologic agonists. The subunit encoded by this gene belongs to
a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole
propionate)-sensitive glutamate receptors, and is subject to RNA
editing (AGA->GGA; R->G). Alternative splicing of this gene results
in transcript variants encoding different isoforms, which may vary
in their signal transduction properties. Some haplotypes of this
gene show a positive association with schizophrenia. [provided by
RefSeq].
Product Categories/Family for anti-GRIA4 antibody
References
Need, A.C., et al. Eur. J. Hum. Genet. 17(7):946-957(2009)
Volpi, S., et al. J Clin Psychiatry 70(6):801-809(2009)
Kessels, H.W., et al. Neuron 61(3):340-350(2009)
Arai, S., et al. Psychiatr. Genet. 19(1):6-13(2009)
Aruscavage, P.J., et al. RNA 6(2):257-269(2000)
Volpi, S., et al. J Clin Psychiatry 70(6):801-809(2009)
Kessels, H.W., et al. Neuron 61(3):340-350(2009)
Arai, S., et al. Psychiatr. Genet. 19(1):6-13(2009)
Aruscavage, P.J., et al. RNA 6(2):257-269(2000)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
100871
NCBI Official Full Name
glutamate receptor 4 isoform 1
NCBI Official Synonym Full Names
glutamate receptor, ionotropic, AMPA 4
NCBI Official Symbol
GRIA4
NCBI Official Synonym Symbols
GLUR4; GLURD; GluA4; GLUR4C
NCBI Protein Information
glutamate receptor 4
UniProt Protein Name
Glutamate receptor 4
UniProt Gene Name
GRIA4
UniProt Synonym Gene Names
GLUR4; GluR-4; GluR4; GluA4
UniProt Entry Name
GRIA4_HUMAN
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Product Notes
The GRIA4 gria4 (Catalog #AAA287084) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 296-325. The GRIA4 Antibody (Center) reacts with Human, mouse (Predicted Reactivity: Monkey, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's GRIA4 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the GRIA4 gria4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GRIA4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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