IHC (Immunohiostchemistry)
(Immunohistochemical staining of human brain tissue using Grik1 antibody at 2.5 ug/mL.)
Rabbit Grik1 Polyclonal Antibody | anti-Grik1 antibody
Grik1 Antibody
Gene Names
GRIK1; EAA3; EEA3; GLR5; GLUR5; GluK1
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
Grik1, Antibody; Grik1 Antibody; Glutamate receptor ionotropic kainate 1, glutamate receptor 5, gluR5, excitatory amino acid receptor 3, eea3; anti-Grik1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
918
Applicable Applications for anti-Grik1 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 16 amino acid peptide near the center of the human Grik1.
Target Name
Grik1
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemical staining of human brain tissue using Grik1 antibody at 2.5 ug/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemical staining of human brain tissue using Grik1 antibody at 2.5 ug/mL.)
WB (Western Blot)
(Western blot analysis of Grik1 in rat brain tissue lysate with Grik1 antibody at (A) 0.5 and (B) 1 ug/mL.)
WB (Western Blot)
(Western blot analysis of Grik1 in rat brain tissue lysate with Grik1 antibody at (A) 0.5 and (B) 1 ug/mL.)
Related Product Information for anti-Grik1 antibody
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik1, also known as glutamate receptor 5, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Grik1 is expressed in GABAergic interneurons of the hippocampus and are thought to participate in the formation of various subtypes of kainate receptors with Grik2 and KA2. Stimulation of Grik1 leads to intracellular calcium release and activation of protein kinase C. Excessive activation has been associated with psychiatric, neurological and neurodegenerative diseases. Numerous isoforms of Grik1 are known to exist and may be subject to RNA editing within the second transmembrane domain, which is thought to alter the properties of ion flow.
Product Categories/Family for anti-Grik1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
102,631 Da
NCBI Official Full Name
glutamate receptor ionotropic, kainate 1 isoform 1
NCBI Official Synonym Full Names
glutamate receptor, ionotropic, kainate 1
NCBI Official Symbol
GRIK1
NCBI Official Synonym Symbols
EAA3; EEA3; GLR5; GLUR5; GluK1
NCBI Protein Information
glutamate receptor ionotropic, kainate 1
UniProt Protein Name
Glutamate receptor ionotropic, kainate 1
UniProt Gene Name
GRIK1
UniProt Synonym Gene Names
GLUR5; GluK1; EAA3; GluR-5; GluR5
UniProt Entry Name
GRIK1_HUMAN
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Product Notes
The Grik1 grik1 (Catalog #AAA302656) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Grik1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Grik1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the Grik1 grik1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Grik1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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