WB (Western Blot)
(Western blot of 10 ug of rathippocampal lysate showing specific immunolabeling of ~180k NR2B subunit of the NMDA receptor)
Rabbit GRIN2B Polyclonal Antibody | anti-GRIN2B antibody
GRIN2B antibody (N-terminus)
Gene Names
GRIN2B; MRD6; NR2B; hNR3; EIEE27; GluN2B; NMDAR2B
Applications
Immunohistochemistry, Western Blot
Purity
GRIN2B antibody was purified by affinity chromatography
Synonyms
GRIN2B, Antibody; GRIN2B antibody (N-terminus); Polyclonal GRIN2B; Anti-GRIN2B; GRIN 2B; GRIN-2B; GRIN2B; Glutamate Receptor Ionotropic N-Methyl D-Aspartate 2B; MGC142178; MGC142180; NMDAR2B; NR2B; hNR3; anti-GRIN2B antibody
Host
Rabbit
Clonality
Polyclonal
Purity/Purification
GRIN2B antibody was purified by affinity chromatography
Form/Format
Supplied in liquid form in 10 mM HEPES buffer (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol
Sequence Length
1484
Applicable Applications for anti-GRIN2B antibody
IHC (Immunohistochemistry), WB (Western Blot)
Biological Significance
NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death.
WB (Western Blot)
(Western blot of 10 ug of rathippocampal lysate showing specific immunolabeling of ~180k NR2B subunit of the NMDA receptor)
WB (Western Blot)
(Western blot of 10 ug of rathippocampal lysate showing specific immunolabeling of ~180k NR2B subunit of the NMDA receptor)
IF (Immunofluorescence)
(Immunofluorescent staining of 14 DIV rat cortical neurons showing NR2B in green andPSD95 in red)
IF (Immunofluorescence)
(Immunofluorescent staining of 14 DIV rat cortical neurons showing NR2B in green andPSD95 in red)
Related Product Information for anti-GRIN2B antibody
Rabbit polyclonal GRIN2B antibody (N-terminus)
Product Categories/Family for anti-GRIN2B antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
166,367 Da
NCBI Official Full Name
glutamate receptor ionotropic, NMDA 2B
NCBI Official Synonym Full Names
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
NCBI Official Symbol
GRIN2B
NCBI Official Synonym Symbols
MRD6; NR2B; hNR3; EIEE27; GluN2B; NMDAR2B
NCBI Protein Information
glutamate receptor ionotropic, NMDA 2B
UniProt Protein Name
Glutamate receptor ionotropic, NMDA 2B
UniProt Gene Name
GRIN2B
UniProt Synonym Gene Names
NMDAR2B; GluN2B; NMDAR2B; NR2B; NR3; hNR3
UniProt Entry Name
NMDE2_HUMAN
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Product Notes
The GRIN2B grin2b (Catalog #AAA107948) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's GRIN2B can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the GRIN2B grin2b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GRIN2B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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