IHC (Immunohistochemistry)
(Anti-GRM5 / MGLUR5 antibody IHC of human colon, myenteric plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Rabbit GRM5 / MGLUR5 Polyclonal Antibody | anti-GRM5 antibody
Rabbit Polyclonal to Human GRM5 / MGLUR5
Gene Names
GRM5; mGlu5; GPRC1E; MGLUR5; PPP1R86
Reactivity
Bat, Gibbon, Bovine, Chicken, Dog, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, RatPredicted Reactivity: Xenopus (at least 90% immunogen sequence identity)
Applications
Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
GRM5 / MGLUR5, Antibody; Rabbit Polyclonal to Human GRM5 / MGLUR5; Anti-GRM5 / MGLUR5 Antibody (N-Terminus) IHC-plus; GRM5; GPRC1E; MGLUR5; Mglur5b; MGlu5; Human GRM5; anti-GRM5 antibody
Host
Rabbit
Reactivity
Bat, Gibbon, Bovine, Chicken, Dog, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Predicted Reactivity: Xenopus (at least 90% immunogen sequence identity)
Predicted Reactivity: Xenopus (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Specificity
Human GRM5 / MGLUR5. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
1180
Applicable Applications for anti-GRM5 antibody
IHC (Immunohistochemistry)
Target Species
Human
Immunogen Description
Synthetic 17 amino acid peptide from N-terminal extracellular domain of human GRM5 / MGLUR5.
Immunogen Type
Synthetic peptide
Immunogen
GRM5 / MGLUR5 antibody was raised against synthetic 17 amino acid peptide from N-terminal extracellular domain of human GRM5 / MGLUR5. Percent identity with other species by BLAST analysis: Human, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Bat, Bovine, Hamster, Horse, Rabbit, Pig, Turkey, Zebra finch, Chicken, Platypus, Lizard (100%); Xenopus (94%); Opossum, Pufferfish (88%); Zebrafish (82%).
Antigen Modification
N-Terminus
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C
IHC (Immunohistochemistry)
(Anti-GRM5 / MGLUR5 antibody IHC of human colon, myenteric plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
IHC (Immunohistochemistry)
(Anti-GRM5 / MGLUR5 antibody IHC of human colon, myenteric plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-GRM5 antibody
Group I of the Metabotropic Glutamate Receptors includes GRM1 and GRM5, receptors that have been shown to activate phospholipase C. Alternative splice variants of GRM5 have been described, but their full-length nature has not been determined. Inflammation results in the activation of mGluR1 and mGluR5 in dorsal horn neurons of the spinal cord, leading to extracellular signal-regulated kinase (ERK) activation, which is required for nociceptive plasticity and enhanced pain.
Product Categories/Family for anti-GRM5 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
105,432 Da
NCBI Official Full Name
metabotropic glutamate receptor 5 isoform b
NCBI Official Synonym Full Names
glutamate receptor, metabotropic 5
NCBI Official Symbol
GRM5
NCBI Official Synonym Symbols
mGlu5; GPRC1E; MGLUR5; PPP1R86
NCBI Protein Information
metabotropic glutamate receptor 5; protein phosphatase 1, regulatory subunit 86
UniProt Protein Name
Metabotropic glutamate receptor 5
UniProt Gene Name
GRM5
UniProt Synonym Gene Names
GPRC1E; MGLUR5; mGluR5
UniProt Entry Name
GRM5_HUMAN
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Product Notes
The GRM5 grm5 (Catalog #AAA50766) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human GRM5 / MGLUR5 reacts with Bat, Gibbon, Bovine, Chicken, Dog, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat Predicted Reactivity: Xenopus (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's GRM5 / MGLUR5 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the GRM5 grm5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GRM5 / MGLUR5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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