IF (Immunofluorescence)
(Immunofluorescence analysis of NIH/3T3 cells using Granulin Rabbit pAb.)
Rabbit anti-Human, Mouse GRN Polyclonal Antibody | anti-GRN antibody
GRN Rabbit Polyclonal Antibody
Gene Names
GRN; GEP; GP88; PEPI; PGRN; CLN11; PCDGF
Reactivity
Human, Mouse
Applications
Immunofluorescence, Western Blot
Purity
Affinity purification
Synonyms
GRN, Antibody; GRN Rabbit Polyclonal Antibody; GRN; CLN11; GEP; GP88; PCDGF; PEPI; PGRN; granulins; anti-GRN antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Applicable Applications for anti-GRN antibody
IF (Immunofluorescence), WB (Western Blot)
Immunogen
Recombinant fusion protein of human Granulin (NP_002078.1).
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
IF (Immunofluorescence)
(Immunofluorescence analysis of NIH/3T3 cells using Granulin Rabbit pAb.)
IF (Immunofluorescence)
(Immunofluorescence analysis of NIH/3T3 cells using Granulin Rabbit pAb.)
WB (Western Blot)
(Western blot analysis of extracts of A-431 cells, using Granulin antibody.)
WB (Western Blot)
(Western blot analysis of extracts of A-431 cells, using Granulin antibody.)
Related Product Information for anti-GRN antibody
Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.
Product Categories/Family for anti-GRN antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
63,544 Da
NCBI Official Full Name
granulin
NCBI Official Synonym Full Names
granulin
NCBI Official Symbol
GRN
NCBI Official Synonym Symbols
GEP; GP88; PEPI; PGRN; CLN11; PCDGF
NCBI Protein Information
granulins; acrogranin; progranulin; proepithelin; granulin-epithelin; PC cell-derived growth factor
UniProt Protein Name
Granulins
UniProt Gene Name
GRN
UniProt Synonym Gene Names
PEPI
UniProt Entry Name
GRN_HUMAN
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Product Notes
The GRN grn (Catalog #AAA313301) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GRN Rabbit Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's GRN can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot). Researchers should empirically determine the suitability of the GRN grn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GRN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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