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product-image-AAA119175_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemistry of paraffin-embedded human esophagus using AAA119175 at dilution 1:100)

Rabbit anti-Human, Rat Growth factor receptor-bound protein 7 Polyclonal Antibody | anti-GRB7 antibody

Rabbit anti-human Growth factor receptor-bound protein 7 polyclonal Antibody(GRB7)

Reactivity
Human, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Antigen Affinity Purified
Synonyms
Growth factor receptor-bound protein 7, Antibody; Rabbit anti-human Growth factor receptor-bound protein 7 polyclonal Antibody(GRB7); B47; Epidermal growth factor receptor GRB-7; GRB7 adapter protein; GRB7; anti-GRB7 antibody
Ordering
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Sequence Length
532
Applicable Applications for anti-GRB7 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Growth factor receptor-bound protein 7 protein (233-532aa)
Immunogen Species
Homo sapiens (Human)
Research Area
Signal Transduction
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-607 / sc-13954 / sc-606
Preparation and Storage
Upon receipt store at -20°C or -80°C. Avoid repeated freeze.

IHC (Immunohiostchemistry)

(Immunohistochemistry of paraffin-embedded human esophagus using AAA119175 at dilution 1:100)

product-image-AAA119175_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemistry of paraffin-embedded human esophagus using AAA119175 at dilution 1:100)

WB (Western Blot)

(All lanes: Growth factor receptor-bound protein 7 antibody at 2ug/ml+rat brain tissueSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 60,50,63,56 kDaObserved band size: 60 kDa)

product-image-AAA119175_WB15.jpg WB (Western Blot) (All lanes: Growth factor receptor-bound protein 7 antibody at 2ug/ml+rat brain tissueSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 60,50,63,56 kDaObserved band size: 60 kDa)
Related Product Information for anti-GRB7 antibody
Adapter protein that interacts with the cytoplasmic domain of numerous receptor kinases and modulates down-stream signaling. Promotes activation of down-stream protein kinases, including STAT3, AKT1, MAPK1 and/or MAPK3. Promotes activation of HRAS. Plays a role in signal transduction in response to EGF. Plays a role in the regulation of cell proliferation and cell migration. Plays a role in the assembly and stability of RNA stress granules. Binds to the 5'UTR of target mRNA molecules and represses translation of target mRNA species, when not phosphorylated. Phosphorylation impairs RNA binding and promotes stress granule disassembly during recovery after cellular stress (By similarity).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
55,920 Da
NCBI Official Full Name
growth factor receptor-bound protein 7 isoform a
NCBI Official Synonym Full Names
growth factor receptor bound protein 7
NCBI Official Symbol
GRB7
NCBI Protein Information
growth factor receptor-bound protein 7
UniProt Protein Name
Growth factor receptor-bound protein 7
UniProt Gene Name
GRB7
UniProt Entry Name
GRB7_HUMAN

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Product Notes

The GRB7 grb7 (Catalog #AAA119175) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Growth factor receptor-bound protein 7 polyclonal Antibody(GRB7) reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Growth factor receptor-bound protein 7 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the GRB7 grb7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Growth factor receptor-bound protein 7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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