IHC (Immunohiostchemistry)
(Immunohistochemistry of HAAO in human liver tissue with HAAO antibody at 2.5 ug/mL.)
Rabbit HAAO Polyclonal Antibody | anti-HAAO antibody
HAAO Antibody
Gene Names
HAAO; HAO; 3-HAO
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
HAAO, Antibody; HAAO Antibody; 3-hydroxyanthranilate 3, 4-dioxygenase, 3-hydroxyanthranilate oxygenase, 3-HAO, HAD, HAO; anti-HAAO antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
286
Applicable Applications for anti-HAAO antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 17 amino acid peptide near the amino terminus of human HAAO.
Target Name
HAAO
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemistry of HAAO in human liver tissue with HAAO antibody at 2.5 ug/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of HAAO in human liver tissue with HAAO antibody at 2.5 ug/mL.)
WB (Western Blot)
(Western blot analysis of HAAO in Mouse liver tissue lysate with HAAO antibody at 1 ug/mL.)
WB (Western Blot)
(Western blot analysis of HAAO in Mouse liver tissue lysate with HAAO antibody at 1 ug/mL.)
Related Product Information for anti-HAAO antibody
HAAO (3-Hydroxyanthranilate 3, 4-dioxygenase) is a monomeric cytosolic protein of the family of intramolecular dioxygenases containing non-heme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is present in low amounts in the central nervous system. This enzyme participates in tryptophan metabolism. It employs one cofactor, iron. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurological and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN. Furthermore, recent study shows that HAAO are excellent candidate biomarkers for detecting ovarian cancer.
Product Categories/Family for anti-HAAO antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
17,275 Da
NCBI Official Full Name
3-hydroxyanthranilate 3,4-dioxygenase
NCBI Official Synonym Full Names
3-hydroxyanthranilate 3,4-dioxygenase
NCBI Official Symbol
HAAO
NCBI Official Synonym Symbols
HAO; 3-HAO
NCBI Protein Information
3-hydroxyanthranilate 3,4-dioxygenase
UniProt Protein Name
3-hydroxyanthranilate 3,4-dioxygenase
UniProt Gene Name
HAAO
UniProt Synonym Gene Names
3-HAO; HAD
UniProt Entry Name
3HAO_HUMAN
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Product Notes
The HAAO haao (Catalog #AAA304082) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HAAO Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's HAAO can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the HAAO haao for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HAAO, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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