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product-image-AAA303948_WB10.jpg WB (Western Blot) (Western blot analysis of extracts from k562 cells (Lane 2), using HDAC5 antiobdy. The lane on the left is treated with synthesized peptide.)

Rabbit HDAC5 Polyclonal Antibody | anti-HDAC5 antibody

HDAC5 Antibody

Gene Names
HDAC5; HD5; NY-CO-9
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunohistochemistry, Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
HDAC5, Antibody; HDAC5 Antibody; Histone deacetylase 5; HD5; Antigen NY-CO-9; anti-HDAC5 antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total HDAC5 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
1123
Applicable Applications for anti-HDAC5 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from human HDAC5.
Target Name
HDAC5
Preparation and Storage
Store at -20 degree C

WB (Western Blot)

(Western blot analysis of extracts from k562 cells (Lane 2), using HDAC5 antiobdy. The lane on the left is treated with synthesized peptide.)

product-image-AAA303948_WB10.jpg WB (Western Blot) (Western blot analysis of extracts from k562 cells (Lane 2), using HDAC5 antiobdy. The lane on the left is treated with synthesized peptide.)

WB (Western Blot)

(Western blot analysis of extracts from HepG2 cells, treated with PMA (125ng/ml, 30mins), using HDAC5 antibody.)

product-image-AAA303948_WB11.jpg WB (Western Blot) (Western blot analysis of extracts from HepG2 cells, treated with PMA (125ng/ml, 30mins), using HDAC5 antibody.)

IF (Immunofluorescence)

(Immunofluorescence analysis of NIH/3T3 cells, using HDAC5 antibody.)

product-image-AAA303948_IF13.jpg IF (Immunofluorescence) (Immunofluorescence analysis of NIH/3T3 cells, using HDAC5 antibody.)

IHC (Immunohistochemistry)

(Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using HDAC5 antibody.)

product-image-AAA303948_IHC15.jpg IHC (Immunohistochemistry) (Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using HDAC5 antibody.)
Related Product Information for anti-HDAC5 antibody
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors.Claudie Lemercier, J. Biol. Chem., May 2000; 275: 15594.Carmen C. Sucharov, Am J Physiol Cell Physiol, Nov 2006; 291: C1029 - C1037.Michael P. Czubryt, PNAS, Feb 2003; 100: 1711.changhoon ha, FASEB J, Apr 2007; 21: A528.
Product Categories/Family for anti-HDAC5 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
122,049 Da
NCBI Official Full Name
histone deacetylase 5 isoform 3
NCBI Official Synonym Full Names
histone deacetylase 5
NCBI Official Symbol
HDAC5
NCBI Official Synonym Symbols
HD5; NY-CO-9
NCBI Protein Information
histone deacetylase 5
UniProt Protein Name
Histone deacetylase 5
UniProt Gene Name
HDAC5
UniProt Synonym Gene Names
KIAA0600; HD5
UniProt Entry Name
HDAC5_HUMAN

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Product Notes

The HDAC5 hdac5 (Catalog #AAA303948) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HDAC5 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's HDAC5 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the HDAC5 hdac5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HDAC5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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