Rabbit HHIP Polyclonal Antibody | anti-HHIP antibody

HHIP Antibody (N-term)

Cat. Num. AAA285427

• Gene Names: HHIP; HIP
• Reactivity: Human (Predicted Reactivity: Mouse)
• Applications: ELISA, Western Blot
• Purity: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
• Synonyms: HHIP, Antibody; HHIP Antibody (N-term); Hedgehog-interacting protein; HHIP; HIP; anti-HHIP antibody

• Host: Rabbit
• Reactivity: Human (Predicted Reactivity: Mouse)
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Specificity: This HHIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the N-terminal region of human HHIP.
• Purity/Purification: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
• Form/Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Sequence Positions: 25-54
• Sequence Length: 320

• Applicable Applications for anti-HHIP antibody: ELISA, WB (Western Blot)
• Antigen Type: Synthetic Peptide
• Antigen Source: HUMAN
• Function: Modulates hedgehog signaling in several cell types including brain and lung through direct interaction with members of the hedgehog family.
• Cellular Location: Cell membrane; Peripheral membrane protein. Secreted. Note=The last 22 C- terminal amino acids may participate in cell membrane attachment
• Tissue Location: Widely expressed in fetal and adult tissues. Highest expression in adult heart, liver and pancreas, and in fetal kidney. {ECO:0000269|PubMed:11435703, ECO:0000269|Ref.1}
• Preparation and Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

WB (Western Blot)

(HHIP Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the HHIP antibody detected the HHIP protein (arrow).)

Related Product Information for anti-HHIP antibody

This gene encodes a protein similar to the mouse
hedgehog-interacting protein, a regulatory component of the
hedgehog signalling pathway. Members of the hedgehog family are
evolutionarily conserved proteins which are involved in many
fundamental processes in embryonic development, including
anteroposterior patterns of limbs and regulation of left-right
asymmetry.

Product Categories/Family for anti-HHIP antibody

Signal Transduction

References

Pillai, S.G., et al. Am. J. Respir. Crit. Care Med. (2010) In press :
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Liu, J.Z., et al. Twin Res Hum Genet 13(2):179-193(2010)
Cho, M.H., et al. Nat. Genet. 42(3):200-202(2010)
Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :

NCBI and Uniprot Product Information

• NCBI GI #: 20143973
• NCBI GeneID: 64399
• NCBI Accession #: NP_071920.1
• NCBI GenBank Nucleotide #: NM_022475.2
• UniProt Accession #: Q96QV1; Q6PK09; Q8NCI7; Q9BXK3; Q9H1J4; Q9H7E7
• Molecular Weight: 78851
• NCBI Official Full Name: hedgehog-interacting protein
• NCBI Official Synonym Full Names: hedgehog interacting protein
• NCBI Official Symbol: HHIP
• NCBI Official Synonym Symbols: HIP
• NCBI Protein Information: hedgehog-interacting protein
• UniProt Protein Name: Hedgehog-interacting protein
• UniProt Gene Name: HHIP
• UniProt Synonym Gene Names: HIP; HHIP; HIP
• UniProt Entry Name: HHIP_HUMAN