Rabbit anti-Human HIG1 Polyclonal Antibody | anti-HIGD1A antibody

HIG1 Antibody

Cat. Num. AAA40275

• Gene Names: HIGD1A; HIG1; RCF1a
• Reactivity: Human
• Applications: Immunofluorescence, Immunocytochemistry, Western Blot, ELISA
• Purity: HIG1 Antibody is affinity chromatography purified via peptide column.
• Synonyms: HIG1, Antibody; HIG1 Antibody; HIG1; RCF1a; HSPC010; HIG1 domain family member 1A; mitochondrial; Hypoxia-inducible gene 1 protein; HIG1 hypoxia inducible domain family, member 1A; anti-HIGD1A antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: HIG1 antibody is predicted to not cross-react with HIG2
• Purity/Purification: HIG1 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 107

• Applicable Applications for anti-HIGD1A antibody: IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: HIG1 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human HIG1.
• Buffer: HIG1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: HIG1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of HIG1 in 293 cells tissue with HIG1 antibody at 10 μg/mL.)

ICC (Immunocytochemistry)

(Immunocytochemistry of HIG1 in 293 cells with HIG1 antibody at 2.5 μg/mL.)

WB (Western Blot)

(Western blot analysis of HIG1 in 293 cell lysate with HIG1 antibody at at (A) 0.5 and (B) 1 μg/mL.)

Related Product Information for anti-HIGD1A antibody

HIG1 Antibody: HIG1 and HIG2 (Hypoxia-inducible gene 1 and 2, respectively) are known to be induced by hypoxic conditions. HIG1 is induced by hypoxia and by glucose deprivation in cultured cells. In addition, tumor xenografts derived from human cervical cancer cells display increased expression of HIG1 and HIG2 when they are deprived of oxygen. Unlike HIG2, which is ubiquitously expressed and might be an activator and target of the canonical Wnt pathway, the function and the mechanisms underlying its regulation of HIG1 still remained unknown. The putative link between hypoxia and an oncogenic signaling pathway might play an important role in tumorigenesis.

NCBI and Uniprot Product Information

• NCBI GI #: 153085461
• NCBI GeneID: 25994
• NCBI Accession #: NP_001093138
• NCBI GenBank Nucleotide #: NM_001099668.1
• UniProt Accession #: Q9Y241; Q9UFZ2
• Molecular Weight: 11,770 Da
• NCBI Official Full Name: HIG1 domain family member 1A, mitochondrial isoform a
• NCBI Official Synonym Full Names: HIG1 hypoxia inducible domain family, member 1A
• NCBI Official Symbol: HIGD1A
• NCBI Official Synonym Symbols: HIG1; RCF1a
• NCBI Protein Information: HIG1 domain family member 1A, mitochondrial; RCF1 homolog A; hypoxia inducible gene 1; HIG1 domain family, member 1A; hypoxia-inducible gene 1 protein
• UniProt Protein Name: HIG1 domain family member 1A, mitochondrial
• UniProt Gene Name: HIGD1A
• UniProt Synonym Gene Names: HIG1; RCF1a
• UniProt Entry Name: HIG1A_HUMAN