WB (Western Blot)
(HIST1H2BJ/HIST1H2BK/HIST3H2BB Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the HIST1H2BJ/HIST1H2BK/HIST3H2BB antibody detected the HIST1H2BJ/HIST1H2BK/HIST3H2BB protein (arrow).)
Rabbit HIST1H2BJ/HIST1H2BK/HIST3H2BB Polyclonal Antibody | anti-HIST1H2BJ antibody
HIST1H2BJ/HIST1H2BK/HIST3H2BB Antibody (C-term)
Gene Names
HIST1H2BJ; H2BJ; H2B/r; H2BFR
Reactivity
Human (Predicted Reactivity: Xenopus, Bovine, Monkey, Mouse)
Applications
ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
HIST1H2BJ/HIST1H2BK/HIST3H2BB, Antibody; HIST1H2BJ/HIST1H2BK/HIST3H2BB Antibody (C-term); Histone H2B type 1-J; Histone H2B1; Histone H2Br; H2B/r; HIST1H2BJ; H2BFR; anti-HIST1H2BJ antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Xenopus, Bovine, Monkey, Mouse)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This HIST1H2BJ/HIST1H2BK/HIST3H2BB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-126 amino acids from the C-terminal region of human HIST1H2BJ/HIST1H2BK/HIST3H2BB.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Sequence Positions
98-126
Sequence Length
126
Applicable Applications for anti-HIST1H2BJ antibody
ELISA, WB (Western Blot)
Calculated MW
13904
Function
Core component of nucleosome.Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to thecellular machineries which require DNA as atemplate. Histones thereby play a central rolein transcription regulation, DNA repair, DNA
replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones,
also called histone code, and nucleosome remodeling.
Preparation and Storage
Maintain refrigerated at 2-8°C for up to 2 weeks.. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(HIST1H2BJ/HIST1H2BK/HIST3H2BB Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the HIST1H2BJ/HIST1H2BK/HIST3H2BB antibody detected the HIST1H2BJ/HIST1H2BK/HIST3H2BB protein (arrow).)
WB (Western Blot)
(HIST1H2BJ/HIST1H2BK/HIST3H2BB Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the HIST1H2BJ/HIST1H2BK/HIST3H2BB antibody detected the HIST1H2BJ/HIST1H2BK/HIST3H2BB protein (arrow).)
Related Product Information for anti-HIST1H2BJ antibody
Histones are basic nuclear proteins that are responsible
for the nucleosome structure of the chromosomal fiber in
eukaryotes. Two molecules of each of the four core histones (H2A,
H2B, H3, and H4) form an octamer, around which approximately 146 bp
of DNA is wrapped in repeating units, called nucleosomes. The
linker histone, H1, interacts with linker DNA between nucleosomes
and functions in the compaction of chromatin into higher order
structures. This gene is intronless and encodes a member of the
histone H2B family. Transcripts from this gene lack polyA tails but
instead contain a palindromic termination element. This gene is
found in the histone microcluster on chromosome 6p21.33. [provided
by RefSeq].
for the nucleosome structure of the chromosomal fiber in
eukaryotes. Two molecules of each of the four core histones (H2A,
H2B, H3, and H4) form an octamer, around which approximately 146 bp
of DNA is wrapped in repeating units, called nucleosomes. The
linker histone, H1, interacts with linker DNA between nucleosomes
and functions in the compaction of chromatin into higher order
structures. This gene is intronless and encodes a member of the
histone H2B family. Transcripts from this gene lack polyA tails but
instead contain a palindromic termination element. This gene is
found in the histone microcluster on chromosome 6p21.33. [provided
by RefSeq].
References
Shi, J., et al. Nature 460(7256):753-757(2009)
Benyamin, B., et al. Am. J. Hum. Genet. 84(1):60-65(2009)
Kim, S.C., et al. Mol. Cell 23(4):607-618(2006)
Beck, H.C., et al. Mol. Cell Proteomics 5(7):1314-1325(2006)
Pavri, R., et al. Cell 125(4):703-717(2006)
Benyamin, B., et al. Am. J. Hum. Genet. 84(1):60-65(2009)
Kim, S.C., et al. Mol. Cell 23(4):607-618(2006)
Beck, H.C., et al. Mol. Cell Proteomics 5(7):1314-1325(2006)
Pavri, R., et al. Cell 125(4):703-717(2006)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
histone H2B type 1-J
NCBI Official Synonym Full Names
histone cluster 1, H2bj
NCBI Official Symbol
HIST1H2BJ
NCBI Official Synonym Symbols
H2BJ; H2B/r; H2BFR
NCBI Protein Information
histone H2B type 1-J
UniProt Protein Name
Histone H2B type 1-J
UniProt Gene Name
HIST1H2BJ
UniProt Synonym Gene Names
H2BFR; H2B/r
UniProt Entry Name
H2B1J_HUMAN
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Product Notes
The HIST1H2BJ hist1h2bj (Catalog #AAA284005) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 98-126. The HIST1H2BJ/HIST1H2BK/HIST3H2BB Antibody (C-term) reacts with Human (Predicted Reactivity: Xenopus, Bovine, Monkey, Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's HIST1H2BJ/HIST1H2BK/HIST3H2BB can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the HIST1H2BJ hist1h2bj for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HIST1H2BJ/HIST1H2BK/HIST3H2BB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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