Rabbit HLA-DRA Polyclonal Antibody | anti-HLA-DRA antibody

HLA-DRA Antibody

Cat. Num. AAA303613

• Gene Names: HLA-DRA; MLRW; HLA-DRA1
• Reactivity: Human, Mouse, Rat
• Applications: Immunohistochemistry, Western Blot
• Purity: Antibodies were purified by affinity purification using immunogen.
• Synonyms: HLA-DRA, Antibody; HLA-DRA Antibody; MLRW; HLA-DRA1; anti-HLA-DRA antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous level of total HLA-DRA protein.
• Purity/Purification: Antibodies were purified by affinity purification using immunogen.
• Form/Format: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1.0 mg/ml (varies by lot)
• Sequence Length: 254

• Applicable Applications for anti-HLA-DRA antibody: IHC (Immunohistochemistry), WB (Western Blot)
• Immunogen Type: Recombinant Protein
• Immunogen Description: Recombinant protein of human HLA-DRA.
• Target Name: HLA-DRA
• Preparation and Storage: Store at -20 degree C

IHC (Immunohistochemistry)

(Immunohistochemical analysis of paraffin-embedded human thyroid cancer using HLA-DRA antibody at dilution of 1:200 (200x lens).)

IHC (Immunohistochemisry)

(Immunohistochemical analysis of paraffin-embedded rat lung using HLA-DRA antibody at dilution of 1:200 (200x lens).)

IHC (Immunohiostchemistry)

(Immunohistochemical analysis of paraffin-embedded mouse lung using HLA-DRA antibody at dilution of 1:200 (200x lens).)

WB (Western Blot)

(Western blot analysis of extracts of Raji and Jurkat cell lines, using HLA-DRA antibody.)

Related Product Information for anti-HLA-DRA antibody

HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5.

Product Categories/Family for anti-HLA-DRA antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 52426774
• NCBI GeneID: 3122
• NCBI Accession #: NP_061984.2
• NCBI GenBank Nucleotide #: NM_019111.4
• UniProt Accession #: P01903; Q30160; Q6IAZ1; Q861I2; Q9TP70; A2BET4
• Molecular Weight: 28,607 Da
• NCBI Official Full Name: HLA class II histocompatibility antigen, DR alpha chain
• NCBI Official Synonym Full Names: major histocompatibility complex, class II, DR alpha
• NCBI Official Symbol: HLA-DRA
• NCBI Official Synonym Symbols: MLRW; HLA-DRA1
• NCBI Protein Information: HLA class II histocompatibility antigen, DR alpha chain
• UniProt Protein Name: HLA class II histocompatibility antigen, DR alpha chain
• UniProt Gene Name: HLA-DRA
• UniProt Synonym Gene Names: HLA-DRA1
• UniProt Entry Name: DRA_HUMAN